Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2003136..2003276 Replicon chromosome
Accession NZ_CP091123
Organism Serratia marcescens strain CM2017_569

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2003180..2003276 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2003136..2003276 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L2D48_RS09530 (L2D48_09530) 1999403..1999648 + 246 WP_000108283.1 DUF2274 domain-containing protein -
L2D48_RS09535 (L2D48_09535) 1999944..2000174 - 231 WP_033638067.1 DNA polymerase III subunit theta -
L2D48_RS09540 (L2D48_09540) 2000515..2001033 + 519 WP_038875847.1 non-heme ferritin -
L2D48_RS09545 (L2D48_09545) 2001327..2001743 + 417 WP_047727770.1 CopC domain-containing protein YobA -
L2D48_RS09550 (L2D48_09550) 2001746..2002627 + 882 WP_038875842.1 copper homeostasis membrane protein CopD -
L2D48_RS09555 (L2D48_09555) 2002697..2003038 + 342 WP_025302452.1 YebY family protein -
- 2003136..2003276 - 141 - - Antitoxin
- 2003180..2003276 + 97 - - Toxin
L2D48_RS09560 (L2D48_09560) 2003355..2003549 - 195 WP_230122566.1 tyrosine-type recombinase/integrase -
L2D48_RS09565 (L2D48_09565) 2003985..2004083 + 99 WP_230122671.1 DUF1367 family protein -
L2D48_RS09570 (L2D48_09570) 2004331..2005140 - 810 WP_139145117.1 hypothetical protein -
L2D48_RS09575 (L2D48_09575) 2006373..2006702 - 330 WP_038875697.1 DUF1493 family protein -
L2D48_RS09580 (L2D48_09580) 2006696..2007154 - 459 WP_048233442.1 hypothetical protein -
L2D48_RS09585 (L2D48_09585) 2007558..2007872 - 315 WP_181421323.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1939269..2011099 71830


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 97 bp

>T232790 NZ_CP091123:2003180-2003276 [Serratia marcescens]
AACAAGCCCTGCATTAAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATAGGAATC
GTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 141 bp

>AT232790 NZ_CP091123:c2003276-2003136 [Serratia marcescens]
AAAAAAAGACCGAATACGATTCCTATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TTAATGCAGGGCTTGTTCAGCCGTGCACTTTAAGAGTAGCCTACCGCGCCAGTTTTGCCAG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References