Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | chpSB/PRK09812-ChpS |
Location | 4682462..4683054 | Replicon | chromosome |
Accession | NZ_CP091122 | ||
Organism | Serratia marcescens strain CM2012_028 |
Toxin (Protein)
Gene name | chpB | Uniprot ID | - |
Locus tag | L2D51_RS22480 | Protein ID | WP_016930358.1 |
Coordinates | 4682704..4683054 (+) | Length | 117 a.a. |
Antitoxin (Protein)
Gene name | chpS | Uniprot ID | - |
Locus tag | L2D51_RS22475 | Protein ID | WP_016930357.1 |
Coordinates | 4682462..4682710 (+) | Length | 83 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
L2D51_RS22455 (L2D51_22455) | 4678282..4678620 | + | 339 | WP_016930352.1 | PTS lactose/cellobiose transporter subunit IIA | - |
L2D51_RS22460 (L2D51_22460) | 4678617..4679924 | + | 1308 | WP_016930353.1 | 6-phospho-beta-glucosidase | - |
L2D51_RS22465 (L2D51_22465) | 4679995..4680975 | + | 981 | WP_016930354.1 | LacI family DNA-binding transcriptional regulator | - |
L2D51_RS22470 (L2D51_22470) | 4681167..4682351 | + | 1185 | WP_004930336.1 | MFS transporter TsgA | - |
L2D51_RS22475 (L2D51_22475) | 4682462..4682710 | + | 249 | WP_016930357.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin |
L2D51_RS22480 (L2D51_22480) | 4682704..4683054 | + | 351 | WP_016930358.1 | type II toxin-antitoxin system ChpB family toxin | Toxin |
L2D51_RS22485 (L2D51_22485) | 4683051..4684334 | - | 1284 | WP_060441380.1 | cytosine deaminase | - |
L2D51_RS22490 (L2D51_22490) | 4684623..4687172 | + | 2550 | WP_239442525.1 | nitrite reductase large subunit NirB | - |
L2D51_RS22495 (L2D51_22495) | 4687169..4687495 | + | 327 | WP_016930361.1 | nitrite reductase small subunit NirD | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 117 a.a. Molecular weight: 12434.44 Da Isoelectric Point: 11.5657
>T232783 WP_016930358.1 NZ_CP091122:4682704-4683054 [Serratia marcescens]
MVKRPVFQRGDLIRVSLNPVVGREQQGDFRPALVLSPREFNALGMVLVAPISQGANFARTAGFTVSLSGSGTATQGVILI
NQVRMMDLAGRSAQFIERAPGEVITDALARLQAIID
MVKRPVFQRGDLIRVSLNPVVGREQQGDFRPALVLSPREFNALGMVLVAPISQGANFARTAGFTVSLSGSGTATQGVILI
NQVRMMDLAGRSAQFIERAPGEVITDALARLQAIID
Download Length: 351 bp
>T232783 NZ_CP128231:c1920212-1919841 [Paraburkholderia bonniea]
ATGATTCTCGTTGATACGTCAGTCTGGATCGACCACATCAACGCTTCTGATCCTATGTTGATTACCCTGCTTGCCGAGGA
GCGCGTGCTGGCTCATCCCTATGTGATAGGCGAGATTTCGCTCGGTAGTTTGCGTTCCCGTGATGTCGTGCTTGGCGCGT
TGCTCGACCTGCCGCGCGCTCCTGTTGCAACACCGGATGAGACGTTTTATCTGATCGAGCGCGAAGGCTTGTTCAATCGC
GGAATCGGATACGTCGACACGTCACTGCTGGCGTCCGCGCGCCTACAACCCGGCATTACCATCTGGACGCGCGATAAGCG
ATTGAAGAAGGTTGCCGATGAACTCAATCTCGGTGCAATGCTGGCGCACTAG
ATGATTCTCGTTGATACGTCAGTCTGGATCGACCACATCAACGCTTCTGATCCTATGTTGATTACCCTGCTTGCCGAGGA
GCGCGTGCTGGCTCATCCCTATGTGATAGGCGAGATTTCGCTCGGTAGTTTGCGTTCCCGTGATGTCGTGCTTGGCGCGT
TGCTCGACCTGCCGCGCGCTCCTGTTGCAACACCGGATGAGACGTTTTATCTGATCGAGCGCGAAGGCTTGTTCAATCGC
GGAATCGGATACGTCGACACGTCACTGCTGGCGTCCGCGCGCCTACAACCCGGCATTACCATCTGGACGCGCGATAAGCG
ATTGAAGAAGGTTGCCGATGAACTCAATCTCGGTGCAATGCTGGCGCACTAG
Antitoxin
Download Length: 83 a.a. Molecular weight: 9083.56 Da Isoelectric Point: 4.5026
>AT232783 WP_016930357.1 NZ_CP091122:4682462-4682710 [Serratia marcescens]
MKVFIKKWGNSAGMLVPSALMNELELQVGQEMDMQVIDGALIIKPVKKRYSLQQLLDGCDGEAPAAADDNWEHMPPAGKE
VW
MKVFIKKWGNSAGMLVPSALMNELELQVGQEMDMQVIDGALIIKPVKKRYSLQQLLDGCDGEAPAAADDNWEHMPPAGKE
VW
Download Length: 249 bp
>AT232783 NZ_CP128231:c1920406-1920209 [Paraburkholderia bonniea]
ATGCGTACGACTATTGCGCTTGATGACGACTTGATCGCCAAGGCTCAAGCCTATACGGGCGTGAAGGAAAAAACGGCGCT
CGTGCGCGAAGCGCTAAAGGCCCTGATCCAGCGTGAAGCCGCGAAACGACTCGCAAATCTTGGCGGTAGCCAACCGGGCA
TCAAGGCCGCACCGCGTCGCCGGCAGAACGCCGAATGA
ATGCGTACGACTATTGCGCTTGATGACGACTTGATCGCCAAGGCTCAAGCCTATACGGGCGTGAAGGAAAAAACGGCGCT
CGTGCGCGAAGCGCTAAAGGCCCTGATCCAGCGTGAAGCCGCGAAACGACTCGCAAATCTTGGCGGTAGCCAACCGGGCA
TCAAGGCCGCACCGCGTCGCCGGCAGAACGCCGAATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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