Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 4682462..4683054 Replicon chromosome
Accession NZ_CP091122
Organism Serratia marcescens strain CM2012_028

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag L2D51_RS22480 Protein ID WP_016930358.1
Coordinates 4682704..4683054 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag L2D51_RS22475 Protein ID WP_016930357.1
Coordinates 4682462..4682710 (+) Length 83 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L2D51_RS22455 (L2D51_22455) 4678282..4678620 + 339 WP_016930352.1 PTS lactose/cellobiose transporter subunit IIA -
L2D51_RS22460 (L2D51_22460) 4678617..4679924 + 1308 WP_016930353.1 6-phospho-beta-glucosidase -
L2D51_RS22465 (L2D51_22465) 4679995..4680975 + 981 WP_016930354.1 LacI family DNA-binding transcriptional regulator -
L2D51_RS22470 (L2D51_22470) 4681167..4682351 + 1185 WP_004930336.1 MFS transporter TsgA -
L2D51_RS22475 (L2D51_22475) 4682462..4682710 + 249 WP_016930357.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
L2D51_RS22480 (L2D51_22480) 4682704..4683054 + 351 WP_016930358.1 type II toxin-antitoxin system ChpB family toxin Toxin
L2D51_RS22485 (L2D51_22485) 4683051..4684334 - 1284 WP_060441380.1 cytosine deaminase -
L2D51_RS22490 (L2D51_22490) 4684623..4687172 + 2550 WP_239442525.1 nitrite reductase large subunit NirB -
L2D51_RS22495 (L2D51_22495) 4687169..4687495 + 327 WP_016930361.1 nitrite reductase small subunit NirD -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(8-114)

Antitoxin

(1-82)


Sequences


Toxin        


Download         Length: 117 a.a.        Molecular weight: 12434.44 Da        Isoelectric Point: 11.5657

>T232783 WP_016930358.1 NZ_CP091122:4682704-4683054 [Serratia marcescens]
MVKRPVFQRGDLIRVSLNPVVGREQQGDFRPALVLSPREFNALGMVLVAPISQGANFARTAGFTVSLSGSGTATQGVILI
NQVRMMDLAGRSAQFIERAPGEVITDALARLQAIID

Download         Length: 351 bp

>T232783 NZ_CP128231:c1920212-1919841 [Paraburkholderia bonniea]
ATGATTCTCGTTGATACGTCAGTCTGGATCGACCACATCAACGCTTCTGATCCTATGTTGATTACCCTGCTTGCCGAGGA
GCGCGTGCTGGCTCATCCCTATGTGATAGGCGAGATTTCGCTCGGTAGTTTGCGTTCCCGTGATGTCGTGCTTGGCGCGT
TGCTCGACCTGCCGCGCGCTCCTGTTGCAACACCGGATGAGACGTTTTATCTGATCGAGCGCGAAGGCTTGTTCAATCGC
GGAATCGGATACGTCGACACGTCACTGCTGGCGTCCGCGCGCCTACAACCCGGCATTACCATCTGGACGCGCGATAAGCG
ATTGAAGAAGGTTGCCGATGAACTCAATCTCGGTGCAATGCTGGCGCACTAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9083.56 Da        Isoelectric Point: 4.5026

>AT232783 WP_016930357.1 NZ_CP091122:4682462-4682710 [Serratia marcescens]
MKVFIKKWGNSAGMLVPSALMNELELQVGQEMDMQVIDGALIIKPVKKRYSLQQLLDGCDGEAPAAADDNWEHMPPAGKE
VW

Download         Length: 249 bp

>AT232783 NZ_CP128231:c1920406-1920209 [Paraburkholderia bonniea]
ATGCGTACGACTATTGCGCTTGATGACGACTTGATCGCCAAGGCTCAAGCCTATACGGGCGTGAAGGAAAAAACGGCGCT
CGTGCGCGAAGCGCTAAAGGCCCTGATCCAGCGTGAAGCCGCGAAACGACTCGCAAATCTTGGCGGTAGCCAACCGGGCA
TCAAGGCCGCACCGCGTCGCCGGCAGAACGCCGAATGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References