Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 61742..62277 Replicon chromosome
Accession NZ_CP091121
Organism Serratia ureilytica strain CM2016_324

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag L2D49_RS00280 Protein ID WP_198772516.1
Coordinates 62002..62277 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag L2D49_RS00275 Protein ID WP_047025978.1
Coordinates 61742..62002 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L2D49_RS00255 (L2D49_00255) 57061..57711 + 651 WP_033645112.1 DcrB-related protein -
L2D49_RS00260 (L2D49_00260) 57752..58357 + 606 WP_069100544.1 glutathione S-transferase -
L2D49_RS00265 (L2D49_00265) 58427..59821 + 1395 WP_240290134.1 L-seryl-tRNA(Sec) selenium transferase -
L2D49_RS00270 (L2D49_00270) 59818..61659 + 1842 WP_240290135.1 selenocysteine-specific translation elongation factor -
L2D49_RS00275 (L2D49_00275) 61742..62002 + 261 WP_047025978.1 ribbon-helix-helix domain-containing protein Antitoxin
L2D49_RS00280 (L2D49_00280) 62002..62277 + 276 WP_198772516.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
L2D49_RS00285 (L2D49_00285) 62458..63705 - 1248 WP_033633516.1 MFS transporter -
L2D49_RS00290 (L2D49_00290) 63923..64915 + 993 WP_046688010.1 acyltransferase -
L2D49_RS00295 (L2D49_00295) 64910..65833 - 924 WP_089195337.1 DJ-1/PfpI family protein -
L2D49_RS00300 (L2D49_00300) 65836..66387 - 552 WP_072626481.1 isochorismatase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10616.42 Da        Isoelectric Point: 10.6066

>T232751 WP_198772516.1 NZ_CP091121:62002-62277 [Serratia ureilytica]
MELKWTSKALPDLARLFEFLALANRTAAANSVKALVAAPKALLDNPRLGERLDEFLPREVRRILVGRYEIRYQVQPATIY
VLRIWHTREER

Download         Length: 276 bp

>T232751 NZ_CP128214:1569209-1569544 [Agrobacterium fabrum]
GTGACGAATAAGAAAGATCACGGAAAAGACGCGGCATTGAAGCGAGCCACCCTGCCGCGCAGGTCGGATTTCACCAAGCA
ATTTATCAAAGACTGGCAACGGCTGAACAATTCCGGGCGTTACGACATGGTGAGACTGAAGGAGATCATGCTCCTTCTTA
TCGCCAACGGCGCGCCGTTACCGACGCAGTTTCGTGACCATGAACTGACCGGAGACTGGCGCGATCACCGGGAATGCCAT
GTCGGCGGGGATTTTCTGTTGATCTACACAGTCGATGAGAAGCAGAACCTTCTCATCTTCACCCGCGCGGGAACGCACGC
CGAGCTTTTCAGGTAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9667.98 Da        Isoelectric Point: 4.5201

>AT232751 WP_047025978.1 NZ_CP091121:61742-62002 [Serratia ureilytica]
MNTKVITAHVPLPLAEKVDEMAAKLDRSRGWIVKQALAAWLEQEEERRRLTLAALADVEQQNVIDHESVEAWAASLDSDE
PLPVPR

Download         Length: 261 bp

>AT232751 NZ_CP128214:1568937-1569212 [Agrobacterium fabrum]
ATGACCGCAAATGCTTATGTAAGAGCGCGCATCGATCAGACACTCAAGGACGACGCGACGGCCGTGCTGGACCGCCTGGG
ACTGACTGTTTCAGATGTCATGCGAATGATGCTGACGCGCATTGCCCGAGAAAAAGCTCTGCCGATAGAACTGACACAAC
CAAACGCTGAAACCCTTGCCGCGATTGAAGAAGCGCGCGCCATCGCGGCGGCCGGGCGCAATCGTTTCGGCACGTCTGAA
GCCTTGTTTGAGGCGCTGGACGCTGGCAAACGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References