Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | cptAB/Cpta(toxin) |
Location | 4165821..4166490 | Replicon | chromosome |
Accession | NZ_CP091120 | ||
Organism | Serratia marcescens strain CM2019_254 |
Toxin (Protein)
Gene name | cptA | Uniprot ID | - |
Locus tag | L2D50_RS19770 | Protein ID | WP_025304123.1 |
Coordinates | 4165821..4166243 (-) | Length | 141 a.a. |
Antitoxin (Protein)
Gene name | cptB | Uniprot ID | A0A8G2G4M4 |
Locus tag | L2D50_RS19775 | Protein ID | WP_004931679.1 |
Coordinates | 4166224..4166490 (-) | Length | 89 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
L2D50_RS19750 (L2D50_19750) | 4161710..4162228 | + | 519 | WP_025304119.1 | flavodoxin FldB | - |
L2D50_RS19755 (L2D50_19755) | 4162266..4163630 | - | 1365 | WP_025304120.1 | cell envelope integrity protein CreD | - |
L2D50_RS19760 (L2D50_19760) | 4163711..4165129 | - | 1419 | WP_089181251.1 | two-component system sensor histidine kinase CreC | - |
L2D50_RS19765 (L2D50_19765) | 4165126..4165821 | - | 696 | WP_025304122.1 | two-component system response regulator CreB | - |
L2D50_RS19770 (L2D50_19770) | 4165821..4166243 | - | 423 | WP_025304123.1 | protein YgfX | Toxin |
L2D50_RS19775 (L2D50_19775) | 4166224..4166490 | - | 267 | WP_004931679.1 | FAD assembly factor SdhE | Antitoxin |
L2D50_RS19780 (L2D50_19780) | 4166811..4167803 | + | 993 | WP_025304124.1 | tRNA-modifying protein YgfZ | - |
L2D50_RS19785 (L2D50_19785) | 4167842..4168339 | - | 498 | WP_025304125.1 | DUF2165 domain-containing protein | - |
L2D50_RS19790 (L2D50_19790) | 4168490..4169164 | - | 675 | WP_033639467.1 | hemolysin III family protein | - |
L2D50_RS19795 (L2D50_19795) | 4169348..4169956 | + | 609 | WP_025304127.1 | HD domain-containing protein | - |
L2D50_RS19800 (L2D50_19800) | 4169996..4170922 | - | 927 | WP_025304128.1 | ribokinase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 141 a.a. Molecular weight: 16525.62 Da Isoelectric Point: 10.8432
>T232749 WP_025304123.1 NZ_CP091120:c4166243-4165821 [Serratia marcescens]
VAQWRCDIRISWRTQLFSLLTHGVLILLILISPWPEGYGPLWLVLLTLVVFQCIRSQKRIAAVQGELRLLADRRFSWHGR
EWRLAKKPWMPGYGLLLTLQPMEGKKRRRLWLASDCMSKEEWRHLRQLLLYPPAGNGEEP
VAQWRCDIRISWRTQLFSLLTHGVLILLILISPWPEGYGPLWLVLLTLVVFQCIRSQKRIAAVQGELRLLADRRFSWHGR
EWRLAKKPWMPGYGLLLTLQPMEGKKRRRLWLASDCMSKEEWRHLRQLLLYPPAGNGEEP
Download Length: 423 bp
>T232749 NZ_CP128214:514083-514352 [Agrobacterium fabrum]
ATGAAGCTCGTCTGGACGCTGAGTTCATGGGACGACTATGAGTTCTGGCAAAGAACCGATGCTCGCATGGTCGAGAAAAT
AAACGATCTTATCCGAAATGCCAAACGCACGCCCTTTGCAGGGCTTGGGAAACCGGAGCCTCTGAAGGGCGATATGGCAG
GATATTGGTCTCGGCGGATTACCGCCGAGCATCGGTTTGTCTACCGTGTATCCGGGTCCGGAAGCGAGCAACGGCTGGAA
GTCATTCAGTGCCGCTTCCATTACCAATAA
ATGAAGCTCGTCTGGACGCTGAGTTCATGGGACGACTATGAGTTCTGGCAAAGAACCGATGCTCGCATGGTCGAGAAAAT
AAACGATCTTATCCGAAATGCCAAACGCACGCCCTTTGCAGGGCTTGGGAAACCGGAGCCTCTGAAGGGCGATATGGCAG
GATATTGGTCTCGGCGGATTACCGCCGAGCATCGGTTTGTCTACCGTGTATCCGGGTCCGGAAGCGAGCAACGGCTGGAA
GTCATTCAGTGCCGCTTCCATTACCAATAA
Antitoxin
Download Length: 89 a.a. Molecular weight: 10387.89 Da Isoelectric Point: 4.7921
>AT232749 WP_004931679.1 NZ_CP091120:c4166490-4166224 [Serratia marcescens]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLNDADKALFIRLLECDDPDLFNWLMNHGAPQDGELQRMVTLIQTRN
KDRGPVAM
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLNDADKALFIRLLECDDPDLFNWLMNHGAPQDGELQRMVTLIQTRN
KDRGPVAM
Download Length: 267 bp
>AT232749 NZ_CP128214:513832-514086 [Agrobacterium fabrum]
ATGGCGAATGTGCGATTTACCGAGTTCAGGCAGAACTTCGCGACCCATTTCGACCGGGTTCTGGAAACCCGCGCGCCATT
GCTCGTCACGCGGCAAGGCAAAGAGGCGGTCGTGGTGCTTGCCGAAGGAGAATATGAGAGCATGCAGGAAACGCTGCATC
TCCTGTCCAACCCGGCAAATGCCTCAAGGCTTCGCGCGTCCATGGGCGAACTTGAGCGCGGTGACACCATCGAGCGGGAT
CCGACCGAAGAATGA
ATGGCGAATGTGCGATTTACCGAGTTCAGGCAGAACTTCGCGACCCATTTCGACCGGGTTCTGGAAACCCGCGCGCCATT
GCTCGTCACGCGGCAAGGCAAAGAGGCGGTCGTGGTGCTTGCCGAAGGAGAATATGAGAGCATGCAGGAAACGCTGCATC
TCCTGTCCAACCCGGCAAATGCCTCAAGGCTTCGCGCGTCCATGGGCGAACTTGAGCGCGGTGACACCATCGAGCGGGAT
CCGACCGAAGAATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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