Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1982910..1983050 Replicon chromosome
Accession NZ_CP091120
Organism Serratia marcescens strain CM2019_254

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1982954..1983050 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1982910..1983050 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L2D50_RS09410 (L2D50_09410) 1978237..1978575 + 339 WP_240275408.1 RidA family protein -
L2D50_RS09415 (L2D50_09415) 1978732..1979685 + 954 WP_049209433.1 prolyl aminopeptidase -
L2D50_RS09420 (L2D50_09420) 1979716..1979946 - 231 WP_043141621.1 DNA polymerase III subunit theta -
L2D50_RS09425 (L2D50_09425) 1980291..1980809 + 519 WP_025302449.1 non-heme ferritin -
L2D50_RS09430 (L2D50_09430) 1981134..1981517 + 384 WP_025302450.1 CopC domain-containing protein YobA -
L2D50_RS09435 (L2D50_09435) 1981520..1982401 + 882 WP_240275409.1 copper homeostasis membrane protein CopD -
L2D50_RS09440 (L2D50_09440) 1982471..1982812 + 342 WP_025302452.1 YebY family protein -
- 1982910..1983050 - 141 - - Antitoxin
- 1982954..1983050 + 97 - - Toxin
L2D50_RS09445 (L2D50_09445) 1983295..1983702 + 408 WP_167324229.1 hypothetical protein -
L2D50_RS09450 (L2D50_09450) 1983838..1984188 + 351 WP_025302454.1 DUF4377 domain-containing protein -
L2D50_RS09455 (L2D50_09455) 1984227..1985063 - 837 WP_167324230.1 aminoglycoside phosphotransferase family protein -
L2D50_RS09460 (L2D50_09460) 1985264..1986463 + 1200 WP_025302456.1 trans-2-enoyl-CoA reductase family protein -
L2D50_RS09465 (L2D50_09465) 1986621..1987184 + 564 WP_025302458.1 DUF2975 domain-containing protein -
L2D50_RS09470 (L2D50_09470) 1987159..1987407 + 249 WP_167324231.1 helix-turn-helix transcriptional regulator -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 97 bp

>T232737 NZ_CP091120:1982954-1983050 [Serratia marcescens]
AACAAGCCCTGCATTAAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATAGGAATC
GTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 141 bp

>AT232737 NZ_CP091120:c1983050-1982910 [Serratia marcescens]
AAAAAAAGACCGAATACGATTCCTATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TTAATGCAGGGCTTGTTCAGCCGTGCACTTTAAGAGTAGCCTACCGCGCCAGTTTTGCCAG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References