Detailed information of TA system TA232711

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 3128028..3128941
• Replicon: chromosome
• Accession: NZ_CP091081
• Organism: Enterobacter roggenkampii strain GD21SC1505

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: L1S38_RS15510
• Protein ID: WP_059361206.1
• Coordinates: 3128468..3128941 (+)
• Length: 158 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: A0A8B2SER9
• Locus tag: L1S38_RS15505
• Protein ID: WP_023327017.1
• Coordinates: 3128028..3128471 (+)
• Length: 148 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L1S38_RS15490 (L1S38_15490)	3123653..3125374	+	1722	WP_250670055.1	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	-
L1S38_RS15495 (L1S38_15495)	3125420..3126124	+	705	WP_250670058.1	leucyl/phenylalanyl-tRNA--protein transferase	-
L1S38_RS15500 (L1S38_15500)	3126409..3126627	+	219	WP_002211347.1	translation initiation factor IF-1	-
L1S38_RS15505 (L1S38_15505)	3128028..3128471	+	444	WP_023327017.1	DUF2384 domain-containing protein	Antitoxin
L1S38_RS15510 (L1S38_15510)	3128468..3128941	+	474	WP_059361206.1	RES domain-containing protein	Toxin
L1S38_RS15515 (L1S38_15515)	3128963..3129517	-	555	WP_059361208.1	type I-F CRISPR-associated endoribonuclease Cas6/Csy4	-
L1S38_RS15520 (L1S38_15520)	3129527..3130525	-	999	WP_059361210.1	type I-F CRISPR-associated protein Csy3	-
L1S38_RS15525 (L1S38_15525)	3130539..3131474	-	936	WP_122008404.1	type I-F CRISPR-associated protein Csy2	-
L1S38_RS15530 (L1S38_15530)	3131471..3132781	-	1311	WP_059361211.1	type I-F CRISPR-associated protein Csy1	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-148)

Antitoxin

• Antitoxin Xre/MbcA/ParS-like, toxin-binding domain (94-144)

Sequences

Toxin

Protein

• Length: 158 a.a.
• Molecular weight: 17467.78 Da
• Isoelectric Point: 5.4786

>T232711 WP_059361206.1 NZ_CP091081:3128468-3128941 [Enterobacter roggenkampii]
MIFYRLVTGRYASGAWSGSGANQYGGRWNHKGHPAVYVSTSISLASLEILVHVRKDTVLNQYQLFSIDIPDDQIDYLDKA
WLPEDWQENPAPVSTMDLGTGWLQANSALALILPSCIIPYENNAILNPLHPAFHSALNSVQQLPFIFDTRLAEKTAP

Nucleotide

• Length: 474 bp

>T232711 NZ_CP128153:256665-257015 [Bacillus sp. DX3.1]
TTGATTGTAAAACGCGGCGACGTGTATTTTGCAGACCTTTCCCCAGTTGTTGGTTCTGAGCAAGGAGGCGTTCGTCCGGT
TCTTGTCATTCAAAATGACATCGGAAATCGTTTTAGTCCGACTGTAATTGTAGCGGCTATTACTGCGCAGATTCAAAAAG
CAAAATTACCCACACATGTGGAAATTGATGCGAAAAAGTACGGATTTGAGAGGGATTCTGTTATTTTGCTCGAACAGATT
CGAACAATCGATAAGCAACGCTTAACGGACAAAATCACTCACTTAGATGAGCTGATGATGAGTCGTGTAGATGAAGCTTT
ACAAATTAGTTTAGGACTAATAGATTTTTAA

Antitoxin

Protein

• Length: 148 a.a.
• Molecular weight: 16352.68 Da
• Isoelectric Point: 7.2062

>AT232711 WP_023327017.1 NZ_CP091081:3128028-3128471 [Enterobacter roggenkampii]
MRTWIPAQKPADNALWRYAGLPANRGMRLIEFLNQGLPVSVLDNIHEWTSMSKADILRVTGINERNVARRKSAGRTLTPD
ESERVARFVRVLDAAVDYFGSKEEAWTWLQAPVRGLGNVAPVDLIATETGALEVTDLIGRLEHGVFA

Nucleotide

• Length: 444 bp

>AT232711 NZ_CP128153:256373-256660 [Bacillus sp. DX3.1]
GTGTCCGAATCAAGTGTAACTACTGAAATCGTGATTCGGTTGCCAAAGCAGATGGTAACAGAATTGGACGTAATTGGAAA
ACTAGAGAATAAGAATCGCCATGAACTAATTTGCCAGGCAACAAAACTGTTATTGCGTCAACATAAGACAAAGAAACGCT
ACCAACATGAATCAATGCGACGTGGGTATATTGAAATGGGAAAAATTAATCTTGGTATTGCATCTGAAGCTTTCTTAGCA
GAGTATGAAGCAGCTCATACAGTAGAACGCTTAGTTAGCGGGGGGTAA

Structures

Antitoxin

• AlphaFold DB: A0A8B2SER9