232696

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4711067..4711436 Replicon chromosome
Accession NZ_CP091078
Organism Xanthomonas arboricola pv. pruni strain R1

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0B2CMD0
Locus tag K9U01_RS20320 Protein ID WP_016904515.1
Coordinates 4711067..4711201 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID V7Z8F2
Locus tag K9U01_RS20325 Protein ID WP_006451340.1
Coordinates 4711284..4711436 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K9U01_RS20305 (K9U01_20305) 4708134..4709078 - 945 WP_039512622.1 MBL fold metallo-hydrolase -
K9U01_RS20310 (K9U01_20310) 4709136..4710425 - 1290 WP_039814994.1 tryptophan--tRNA ligase -
K9U01_RS20315 (K9U01_20315) 4710607..4710816 - 210 WP_039512625.1 CsbD family protein -
K9U01_RS20320 (K9U01_20320) 4711067..4711201 - 135 WP_016904515.1 entericidin A/B family lipoprotein Toxin
K9U01_RS20325 (K9U01_20325) 4711284..4711436 - 153 WP_006451340.1 entericidin A/B family lipoprotein Antitoxin
K9U01_RS20330 (K9U01_20330) 4711546..4712469 - 924 WP_039512664.1 arginase -
K9U01_RS20335 (K9U01_20335) 4712945..4713397 + 453 WP_039512628.1 roadblock/LC7 domain-containing protein -
K9U01_RS20340 (K9U01_20340) 4713461..4713820 + 360 WP_039512630.1 hypothetical protein -
K9U01_RS20345 (K9U01_20345) 4713914..4714831 + 918 WP_039512632.1 hypothetical protein -
K9U01_RS20350 (K9U01_20350) 4714828..4715370 + 543 WP_016904520.1 GTPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4443.26 Da        Isoelectric Point: 9.3487

>T232696 WP_016904515.1 NZ_CP091078:c4711201-4711067 [Xanthomonas arboricola pv. pruni]
MKRAIVLLVLSVLSVGMLSGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T232696 NZ_CP128112:245888-246238 [Bacillus mycoides]
TTGATTGTAAAACGCGGCGACGTGTATTTTGCAGACCTTTCCCCAGTTGTTGGTTCTGAGCAAGGAGGCGTTCGTCCGGT
TCTTGTCATTCAAAATGACATCGGAAATCGTTTTAGTCCGACTGTGATTGTAGCGGCTATTACTGCACAGATTCAAAAAG
CGAAATTACCCACTCATGTGGAAATTGATGCGAAAAAGTACGGTTTTGAGAGGGATTCTGTTATTTTACTTGAGCAGATT
CGAACAATCGATAAGCAACGCTTAACGGACAAAATCACTCATTTGGATGAAGTGATGATGAGTCGTGTAGATGAAGCGTT
ACAAATTAGTTTAGGACTAATAGATTTTTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5168.11 Da        Isoelectric Point: 8.2782

>AT232696 WP_006451340.1 NZ_CP091078:c4711436-4711284 [Xanthomonas arboricola pv. pruni]
MKRLLTLMVLGLFSAGVMTGCNTMAGAGKDMQGAGEKVEKKADNCSDGKC

Download         Length: 153 bp

>AT232696 NZ_CP128112:245596-245883 [Bacillus mycoides]
GTGTCCGAATCAAGTGTAACTACTGAAATCGTGGTTCGGTTGCCAAAGCAAATGGTAACGGAATTGGACGGAATTGGAAA
ACAAGAGAATAAGAATCGCCATGAACTAATTTGCCAGGCAACACAACTGTTATTGCGTCAACATAAGACGAAGAAACGCT
ACCAACATGAATCAATGCGACGTGGGTACATTGAAATGGGAAAAATTAATCTTGGTATTGCATCTGAAGCTTTCTTAGCA
GAGTATGAAGCAGCTCATACAGTAGAACGCTTAGTTAGCGGGGGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0B2CMD0

Antitoxin

Source ID Structure
AlphaFold DB A0A2N7V051

References