Detailed information of TA system TA232695

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/Phd(antitoxin)
• Location: 72626..73170
• Replicon: chromosome
• Accession: NZ_CP091078
• Organism: Xanthomonas arboricola pv. pruni strain R1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: K9U01_RS00265
• Protein ID: WP_228960823.1
• Coordinates: 72901..73170 (+)
• Length: 90 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A2N7V9L6
• Locus tag: K9U01_RS00260
• Protein ID: WP_016902922.1
• Coordinates: 72626..72883 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
K9U01_RS00245 (K9U01_00245)	67734..69242	-	1509	WP_043087410.1	ribonuclease H-like domain-containing protein	-
K9U01_RS00250 (K9U01_00250)	69239..71734	-	2496	WP_043087409.1	DEAD/DEAH box helicase	-
K9U01_RS00255 (K9U01_00255)	71908..72570	+	663	WP_039511099.1	hemolysin III family protein	-
K9U01_RS00260 (K9U01_00260)	72626..72883	+	258	WP_016902922.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
K9U01_RS00265 (K9U01_00265)	72901..73170	+	270	WP_228960823.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
K9U01_RS00270 (K9U01_00270)	73289..73810	-	522	WP_051633992.1	hypothetical protein	-
K9U01_RS00275 (K9U01_00275)	73981..74334	-	354	WP_081327586.1	helix-turn-helix domain-containing protein	-
K9U01_RS00280 (K9U01_00280)	74367..74573	+	207	WP_223571151.1	hypothetical protein	-
K9U01_RS00285 (K9U01_00285)	74733..75824	-	1092	WP_039511112.1	ATP-grasp fold amidoligase family protein	-
K9U01_RS00290 (K9U01_00290)	76282..76995	+	714	WP_039511101.1	hypothetical protein	-
K9U01_RS00295 (K9U01_00295)	77006..77899	-	894	WP_043087408.1	LysR family transcriptional regulator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (2-80)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 90 a.a.
• Molecular weight: 10221.75 Da
• Isoelectric Point: 10.1539

>T232695 WP_228960823.1 NZ_CP091078:72901-73170 [Xanthomonas arboricola pv. pruni]
VADLDAIADYIALEDAAAAAALVRRVFAHVEQLAEHPESGSRPQELKRSRYRQIVEPPCRVFYRVDGQRVVVVHVMRSER
LLRKNRLSR

Nucleotide

• Length: 270 bp

>T232695 NZ_CP128109:618575-618925 [Bacillus altitudinis]
TTGATTGTTAAACGCGGTGATGTTTACTTTGCTGATTTATCTCCTGTTGTTGGCTCCGAGCAGGGCGGGGTTCGCCCGGT
ATTGGTGATTCAAAATGACATTGGAAATCGCTTCAGCCCGACTGCTATCGTTGCAGCCATAACAGCCCAAATACAAAAAG
CGAAATTACCGACTCACGTCGAAATTAATGCAAAGCGCTACGGCTTTGAACGAGATTCTGTCATTCTTTTGGAACAGATT
CGTACGATCGATAAACAAAGATTGACAGATAAAATCACACATCTTGATGATGAGATGATGGAGAAGGTTGATGAAGCCTT
ACAAGTTAGTTTGGCTCTTATTGATTTTTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9704.23 Da
• Isoelectric Point: 8.6056

>AT232695 WP_016902922.1 NZ_CP091078:72626-72883 [Xanthomonas arboricola pv. pruni]
MRTELVTTLKRQATELLADVERDKEPILITQHGLPSAYLVDVASYERMQQRMAILEGIARGEMAVAEGRSLSHEQAKQRL
ARWLK

Nucleotide

• Length: 258 bp

>AT232695 NZ_CP128109:618289-618570 [Bacillus altitudinis]
TTGTCTGAATCCAGCGCAACAAACGAAATGAAGATTCGACTGCCGGAGGCTTTAATGTCTGAGATCGAACGAGTAGCAGA
GCAGGATAAGGTAACAAGAAATGAATTGATCTACCGAGCGACAAAAACGTATATTCGTGAACGTAATATTCGACAAAATC
GTGAATCGATGAGACGCGGCTACATGGAGATGGCGAAAATTAATCTGAATATCTCTTCAGAGGCACAATACGCAGAATTT
GAGGCTGAGAATACAGTTGAGCGATTAGTCAGCGGGGGTTAA

Structures

Antitoxin

• AlphaFold DB: A0A2N7V9L6