232691

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 1517878..1518247 Replicon chromosome
Accession NZ_CP091075
Organism Xanthomonas arboricola pv. pruni strain T1

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0B2CMD0
Locus tag K9U02_RS06565 Protein ID WP_016904515.1
Coordinates 1517878..1518012 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID V7Z8F2
Locus tag K9U02_RS06570 Protein ID WP_006451340.1
Coordinates 1518095..1518247 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K9U02_RS06550 (K9U02_06550) 1514945..1515889 - 945 WP_039512622.1 MBL fold metallo-hydrolase -
K9U02_RS06555 (K9U02_06555) 1515947..1517236 - 1290 WP_039814994.1 tryptophan--tRNA ligase -
K9U02_RS06560 (K9U02_06560) 1517418..1517627 - 210 WP_039512625.1 CsbD family protein -
K9U02_RS06565 (K9U02_06565) 1517878..1518012 - 135 WP_016904515.1 entericidin A/B family lipoprotein Toxin
K9U02_RS06570 (K9U02_06570) 1518095..1518247 - 153 WP_006451340.1 entericidin A/B family lipoprotein Antitoxin
K9U02_RS06575 (K9U02_06575) 1518357..1519280 - 924 WP_039512664.1 arginase -
K9U02_RS06580 (K9U02_06580) 1519756..1520208 + 453 WP_039512628.1 roadblock/LC7 domain-containing protein -
K9U02_RS06585 (K9U02_06585) 1520272..1520631 + 360 WP_039512630.1 hypothetical protein -
K9U02_RS06590 (K9U02_06590) 1520725..1521642 + 918 WP_039512632.1 hypothetical protein -
K9U02_RS06595 (K9U02_06595) 1521639..1522181 + 543 WP_016904520.1 GTPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4443.26 Da        Isoelectric Point: 9.3487

>T232691 WP_016904515.1 NZ_CP091075:c1518012-1517878 [Xanthomonas arboricola pv. pruni]
MKRAIVLLVLSVLSVGMLSGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T232691 NZ_CP127882:72124-72522 [Serratia marcescens]
ATGTTGAAGTACCTGCTGGACACCAACACGTGCATCTTCACCATCAAGAACAAACCCGCGCACGTCAGGGAGCGCTTCAG
CCTGAATACGTCGCGCCTGTGCATCAGTTCGGTCACGTTGATGGAGCTGATTTACGGTGCAGAAAAGAGCCAGGCACCAG
AGCGCAACCTGGCTGTGCTCGAAGGGTTCATCGCGCGCCTCGACGTTCTGAACTACGATGCGGCCGCCGCCGCGCACAGC
GGCCAAATTCGGGCCGAATTGAGTCGGCAAGGCCTCCCCATTGGCCCATTTGATTTGATGATTGCCGGCCACGCTCGCAG
CCAGGGACTGATCGTTGTCACCAACCACACGCGGGAGTTTGCACGGGTTGACGGGTTGCGCATCGAAGATTGGTGCTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5168.11 Da        Isoelectric Point: 8.2782

>AT232691 WP_006451340.1 NZ_CP091075:c1518247-1518095 [Xanthomonas arboricola pv. pruni]
MKRLLTLMVLGLFSAGVMTGCNTMAGAGKDMQGAGEKVEKKADNCSDGKC

Download         Length: 153 bp

>AT232691 NZ_CP127882:71897-72124 [Serratia marcescens]
ATGGAAACAACCGTATTTCTCAGCAACCGTAGCCAGGCCGTTCGTCTGCCCAAAGCGGTGGCACTGCCTGAAGACGTTAA
ACGCGTAGAAGTCATCGCCGTTGGTCGCACGCGCATCATTACGCCGGCCGGCGAGGGCTGGGACAGTTGGTTCGACGGTG
AGGATGTCAGCGCCGATTTCATGACGTCGCGCGACCAACCGCCGATGCAAGAGCGGGAGGCGTTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0B2CMD0

Antitoxin

Source ID Structure
AlphaFold DB A0A2N7V051

References