Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2016065..2016210 Replicon chromosome
Accession NZ_CP091068
Organism Klebsiella pneumoniae strain WSCRKP

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2016101..2016203 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2016065..2016210 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0980_RS09835 (L0980_09835) 2011195..2013255 + 2061 WP_004151449.1 oligopeptidase B -
L0980_RS09840 (L0980_09840) 2013259..2013918 - 660 WP_002911407.1 exodeoxyribonuclease X -
L0980_RS09845 (L0980_09845) 2013997..2014227 - 231 WP_002911406.1 DNA polymerase III subunit theta -
L0980_RS09850 (L0980_09850) 2014340..2014714 + 375 WP_004151448.1 CopC domain-containing protein YobA -
L0980_RS09855 (L0980_09855) 2014718..2015587 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
L0980_RS09860 (L0980_09860) 2015604..2015942 + 339 WP_002911404.1 YebY family protein -
- 2016065..2016210 - 146 - - Antitoxin
- 2016101..2016203 + 103 - - Toxin
L0980_RS09865 (L0980_09865) 2016578..2016721 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
L0980_RS09870 (L0980_09870) 2016826..2017794 - 969 WP_004151446.1 VirK/YbjX family protein -
L0980_RS09875 (L0980_09875) 2017951..2018604 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
L0980_RS09880 (L0980_09880) 2018601..2018792 - 192 WP_002911395.1 YebW family protein -
L0980_RS09885 (L0980_09885) 2018890..2019129 - 240 WP_002911393.1 YebV family protein -
L0980_RS09890 (L0980_09890) 2019245..2020678 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T232667 NZ_CP091068:2016101-2016203 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT232667 NZ_CP091068:c2016210-2016065 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References