Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2071043..2071188 Replicon chromosome
Accession NZ_CP091061
Organism Klebsiella pneumoniae strain KP29105

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2071079..2071181 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2071043..2071188 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L1062_RS09910 2066173..2068233 + 2061 WP_004151449.1 oligopeptidase B -
L1062_RS09915 2068237..2068896 - 660 WP_002911407.1 exodeoxyribonuclease X -
L1062_RS09920 2068975..2069205 - 231 WP_002911406.1 DNA polymerase III subunit theta -
L1062_RS09925 2069318..2069692 + 375 WP_004151448.1 CopC domain-containing protein YobA -
L1062_RS09930 2069696..2070565 + 870 WP_014907333.1 copper homeostasis membrane protein CopD -
L1062_RS09935 2070582..2070920 + 339 WP_002911404.1 YebY family protein -
- 2071043..2071188 - 146 - - Antitoxin
- 2071079..2071181 + 103 - - Toxin
L1062_RS09940 2071556..2071699 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
L1062_RS09945 2071804..2072772 - 969 WP_014907334.1 VirK/YbjX family protein -
L1062_RS09950 2072929..2073582 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
L1062_RS09955 2073579..2073770 - 192 WP_002911395.1 YebW family protein -
L1062_RS09960 2073868..2074107 - 240 WP_002911393.1 YebV family protein -
L1062_RS09965 2074223..2075656 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T232592 NZ_CP091061:2071079-2071181 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT232592 NZ_CP091061:c2071188-2071043 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References