Detailed information of TA system TA232568

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-StbC
• Location: 1400633..1401288
• Replicon: chromosome
• Accession: NZ_CP091056
• Organism: Ornithinimicrobium sp. INDO-MA30-4

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: L0A91_RS08070
• Protein ID: WP_129702391.1
• Coordinates: 1400633..1401058 (-)
• Length: 142 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: L0A91_RS08075
• Protein ID: WP_235243782.1
• Coordinates: 1401055..1401288 (-)
• Length: 78 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L0A91_RS08040 (L0A91_08040)	1395829..1395990	+	162	WP_235243774.1	hypothetical protein	-
L0A91_RS08045 (L0A91_08045)	1396188..1396649	-	462	WP_235243776.1	hypothetical protein	-
L0A91_RS08050 (L0A91_08050)	1396890..1397278	-	389	Protein_1612	heavy metal-responsive transcriptional regulator	-
L0A91_RS08055 (L0A91_08055)	1397384..1398806	+	1423	Protein_1613	mercury(II) reductase	-
L0A91_RS08060 (L0A91_08060)	1399101..1399994	+	894	WP_235243778.1	chromosome condensation regulator	-
L0A91_RS08065 (L0A91_08065)	1400085..1400636	-	552	WP_235243780.1	GNAT family N-acetyltransferase	-
L0A91_RS08070 (L0A91_08070)	1400633..1401058	-	426	WP_129702391.1	type II toxin-antitoxin system VapC family toxin	Toxin
L0A91_RS08075 (L0A91_08075)	1401055..1401288	-	234	WP_235243782.1	toxin-antitoxin system	Antitoxin
L0A91_RS08080 (L0A91_08080)	1401454..1403715	-	2262	WP_235243784.1	hypothetical protein	-
L0A91_RS08085 (L0A91_08085)	1403712..1404476	-	765	WP_235243786.1	hypothetical protein	-
L0A91_RS08090 (L0A91_08090)	1404744..1405091	-	348	WP_235243787.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (2-128)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 142 a.a.
• Molecular weight: 15139.17 Da
• Isoelectric Point: 4.6172

>T232568 WP_129702391.1 NZ_CP091056:c1401058-1400633 [Ornithinimicrobium sp. INDO-MA30-4]
MIVLDTNVISEIFRPSPEPRVVEWLVSLTGDVAITSITLAELLAGVRRLPNGQRKDELAQRIDEAVAPYRGSRSVLAFDA
DAAERYAEVLASREAAGAPVSTADAQIAAICLAHGATCATRNVKDFQHTGVELVDPWKVDA

Nucleotide

• Length: 426 bp

>T232568 NZ_CP127378:3990870-3991004 [Xanthomonas fragariae]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGGTGTTGTCGGTCGGTATACTGTCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCTGGCGAGAAGGTGGAAGACGCTGCGCGCAAGTGA

Antitoxin

Protein

• Length: 78 a.a.
• Molecular weight: 8430.54 Da
• Isoelectric Point: 5.5941

>AT232568 WP_235243782.1 NZ_CP091056:c1401288-1401055 [Ornithinimicrobium sp. INDO-MA30-4]
MSSIIVRGLDDHVKQQLSSQAKEHGRSMEAEVRDILTKAARRPHIGMALLSAARDVDGVDELPIPTRDDVARAADLE

Nucleotide

• Length: 234 bp

>AT232568 NZ_CP127378:3990638-3990790 [Xanthomonas fragariae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACTGGCTGTAACACCTTTGCTGGCGC
CGGCAAGGATATGCAACGCGCGGGCAGCAAGGTCGAAAAGAAGGCCGATAACTGCAGCGACGGTAAGTGCTGA