Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2174752..2175023 Replicon chromosome
Accession NZ_CP091044
Organism Escherichia coli strain STEC346

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2174882..2174985 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2174752..2175023 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L1P11_RS10665 2171307..2171969 - 663 WP_000944256.1 exodeoxyribonuclease X -
L1P11_RS10670 2171993..2172649 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
L1P11_RS10675 2172751..2172981 - 231 WP_000916763.1 DNA polymerase III subunit theta -
L1P11_RS10680 2173120..2173494 + 375 WP_000204699.1 CopC domain-containing protein YobA -
L1P11_RS10685 2173498..2174370 + 873 WP_000879334.1 copper homeostasis membrane protein CopD -
L1P11_RS10690 2174383..2174724 + 342 WP_000976492.1 YebY family protein -
- 2174752..2175023 - 272 - - Antitoxin
- 2174882..2174985 + 104 - - Toxin
L1P11_RS10695 2175120..2175776 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
L1P11_RS10700 2175777..2175968 - 192 WP_001296140.1 YebW family protein -
L1P11_RS10705 2176073..2176309 - 237 WP_001295499.1 YebV family protein -
L1P11_RS10710 2176427..2177866 - 1440 WP_000057024.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T232520 NZ_CP091044:2174882-2174985 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT232520 NZ_CP091044:c2175023-2174752 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References