Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2022040..2022308 | Replicon | chromosome |
| Accession | NC_011601 | ||
| Organism | Escherichia coli O127:H6 str. E2348/69 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2022078..2022180 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2022040..2022308 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| E2348C_RS10475 (E2348_C_1960) | 2019197..2020636 | + | 1440 | WP_001339709.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
| E2348C_RS10480 (E2348_C_1961) | 2020754..2020990 | + | 237 | WP_001295499.1 | DUF1480 family protein | - |
| E2348C_RS10485 (E2348_C_1962) | 2021095..2021286 | + | 192 | WP_001296140.1 | YebW family protein | - |
| E2348C_RS10490 (E2348_C_1963) | 2021287..2021943 | - | 657 | WP_000812706.1 | protein-serine/threonine phosphatase | - |
| - | 2022040..2022308 | + | 269 | - | - | Antitoxin |
| - | 2022078..2022180 | - | 103 | - | - | Toxin |
| E2348C_RS10500 (E2348_C_1964) | 2022338..2022679 | - | 342 | WP_000976470.1 | YebY family protein | - |
| E2348C_RS10505 (E2348_C_1965) | 2022692..2023564 | - | 873 | WP_000879263.1 | copper homeostasis membrane protein CopD | - |
| E2348C_RS10510 (E2348_C_1966) | 2023568..2023942 | - | 375 | WP_000204700.1 | CopC domain-containing protein YobA | - |
| E2348C_RS10515 (E2348_C_1967) | 2024081..2024311 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| E2348C_RS10520 (E2348_C_1968) | 2024413..2025069 | + | 657 | WP_000011646.1 | carbon-nitrogen hydrolase family protein | - |
| E2348C_RS10525 (E2348_C_1969) | 2025093..2025755 | + | 663 | WP_000944249.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T23252 NC_011601:c2022180-2022078 [Escherichia coli O127:H6 str. E2348/69]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT
Antitoxin
Download Length: 269 bp
>AT23252 NC_011601:2022040-2022308 [Escherichia coli O127:H6 str. E2348/69]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGGGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGGGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT
