Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2144099..2144370 Replicon chromosome
Accession NZ_CP091026
Organism Escherichia coli strain STEC383

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2144229..2144332 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2144099..2144370 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L1P12_RS10295 2140654..2141316 - 663 WP_000944256.1 exodeoxyribonuclease X -
L1P12_RS10300 2141340..2141996 - 657 WP_000011657.1 carbon-nitrogen hydrolase family protein YobB -
L1P12_RS10305 2142098..2142328 - 231 WP_000916763.1 DNA polymerase III subunit theta -
L1P12_RS10310 2142467..2142841 + 375 WP_000168747.1 CopC domain-containing protein YobA -
L1P12_RS10315 2142845..2143717 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
L1P12_RS10320 2143730..2144071 + 342 WP_000976476.1 YebY family protein -
- 2144099..2144370 - 272 - - Antitoxin
- 2144229..2144332 + 104 - - Toxin
L1P12_RS10325 2144467..2145123 + 657 WP_053885983.1 protein-serine/threonine phosphatase -
L1P12_RS10330 2145124..2145315 - 192 WP_001296140.1 YebW family protein -
L1P12_RS10335 2145420..2145656 - 237 WP_001295499.1 YebV family protein -
L1P12_RS10340 2145774..2147213 - 1440 WP_024174420.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T232453 NZ_CP091026:2144229-2144332 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT232453 NZ_CP091026:c2144370-2144099 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References