Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2156721..2156992 Replicon chromosome
Accession NZ_CP091024
Organism Escherichia coli strain STEC379

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2156851..2156954 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2156721..2156992 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L1P13_RS10625 2153276..2153938 - 663 WP_235399518.1 exodeoxyribonuclease X -
L1P13_RS10630 2153962..2154618 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
L1P13_RS10635 2154720..2154950 - 231 WP_000916763.1 DNA polymerase III subunit theta -
L1P13_RS10640 2155089..2155463 + 375 WP_000204699.1 CopC domain-containing protein YobA -
L1P13_RS10645 2155467..2156339 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
L1P13_RS10650 2156352..2156693 + 342 WP_000976492.1 YebY family protein -
- 2156721..2156992 - 272 - - Antitoxin
- 2156851..2156954 + 104 - - Toxin
L1P13_RS10655 2157089..2157745 + 657 WP_000812720.1 protein-serine/threonine phosphatase -
L1P13_RS10660 2157746..2157937 - 192 WP_001296140.1 YebW family protein -
L1P13_RS10665 2158042..2158278 - 237 WP_001295499.1 YebV family protein -
L1P13_RS10670 2158396..2159835 - 1440 WP_001512833.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T232424 NZ_CP091024:2156851-2156954 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT232424 NZ_CP091024:c2156992-2156721 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGTAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References