Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2060066..2060334 Replicon chromosome
Accession NZ_CP091022
Organism Escherichia coli strain STEC276

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2060193..2060296 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2060066..2060334 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L1O93_RS09870 2056619..2057281 - 663 WP_000944256.1 exodeoxyribonuclease X -
L1O93_RS09875 2057305..2057961 - 657 WP_000011660.1 carbon-nitrogen hydrolase family protein YobB -
L1O93_RS09880 2058063..2058293 - 231 WP_000916763.1 DNA polymerase III subunit theta -
L1O93_RS09885 2058432..2058806 + 375 WP_000168739.1 CopC domain-containing protein YobA -
L1O93_RS09890 2058810..2059682 + 873 WP_000879277.1 copper homeostasis membrane protein CopD -
L1O93_RS09895 2059695..2060036 + 342 WP_001515445.1 YebY family protein -
- 2060066..2060334 - 269 - - Antitoxin
- 2060193..2060296 + 104 - - Toxin
L1O93_RS09900 2060431..2061087 + 657 WP_001515444.1 protein-serine/threonine phosphatase -
L1O93_RS09905 2061088..2061279 - 192 WP_001296140.1 YebW family protein -
L1O93_RS09910 2061384..2061620 - 237 WP_001295499.1 YebV family protein -
L1O93_RS09915 2061738..2063177 - 1440 WP_024189843.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - stx2A / stx2B 1992559..2076172 83613


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T232394 NZ_CP091022:2060193-2060296 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT232394 NZ_CP091022:c2060334-2060066 [Escherichia coli]
AAAGTCAGCGAAGGGAATGTTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References