Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3623122..3623775 Replicon chromosome
Accession NC_011586
Organism Acinetobacter baumannii AB0057

Toxin (Protein)


Gene name cptA Uniprot ID B0V6V2
Locus tag AB57_RS17700 Protein ID WP_000931890.1
Coordinates 3623122..3623511 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag AB57_RS17705 Protein ID WP_001288210.1
Coordinates 3623518..3623775 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AB57_RS17685 3618240..3620435 - 2196 WP_001158905.1 TRAP transporter large permease subunit -
AB57_RS17690 3620623..3621189 - 567 WP_000651536.1 rhombosortase -
AB57_RS17695 3621267..3622352 - 1086 WP_000049106.1 hypothetical protein -
AB57_RS17700 3623122..3623511 - 390 WP_000931890.1 membrane protein Toxin
AB57_RS17705 3623518..3623775 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
AB57_RS17710 3623963..3625135 + 1173 WP_001190546.1 acyl-CoA dehydrogenase family protein -
AB57_RS17715 3625185..3626675 - 1491 WP_000415133.1 NAD(P)/FAD-dependent oxidoreductase -
AB57_RS17720 3626856..3627233 - 378 WP_001216378.1 50S ribosomal protein L17 -
AB57_RS17725 3627252..3628259 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15649.98 Da        Isoelectric Point: 10.4623

>T23238 WP_000931890.1 NC_011586:c3623511-3623122 [Acinetobacter baumannii AB0057]
MLNHLNFKLKYSRFSIIFQFFIGLSLAILFYQLMPLLWWLVVISLLFISFIFFLKRPQLAKIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

>T23238 NC_011586:c3623511-3623122 [Acinetobacter baumannii AB0057]
TTGCTCAACCATTTGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AATTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATAAGCTTTATTTTCTTTT
TAAAGCGTCCGCAACTTGCAAAAATTGCCTATTTAGATAAAAAACTATGGTCGCTTGCTTATCACTCACAGAACACCATT
TCTCGCGTCAAAATTTTAAAAATAATTGATTATCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGCAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT23238 WP_001288210.1 NC_011586:c3623775-3623518 [Acinetobacter baumannii AB0057]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp

>AT23238 NC_011586:c3623775-3623518 [Acinetobacter baumannii AB0057]
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTT
TGACCCTTATGTGAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCGTTGTTTGCTGAGTTGGTAGAACAGGAAG
ATCCTGATTTACTCGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAA
CACTATGTTCATGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0J1A4U0

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References