Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2202694..2202928 Replicon chromosome
Accession NZ_CP091020
Organism Escherichia coli strain STEC308

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2202824..2202927 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2202694..2202928 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L1O95_RS10835 2199249..2199911 - 663 WP_000944256.1 exodeoxyribonuclease X -
L1O95_RS10840 2199935..2200591 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
L1O95_RS10845 2200693..2200923 - 231 WP_000916763.1 DNA polymerase III subunit theta -
L1O95_RS10850 2201062..2201436 + 375 WP_000204699.1 CopC domain-containing protein YobA -
L1O95_RS10855 2201440..2202312 + 873 WP_033813010.1 copper homeostasis membrane protein CopD -
L1O95_RS10860 2202325..2202666 + 342 WP_000976492.1 YebY family protein -
- 2202694..2202928 - 235 - - Antitoxin
- 2202824..2202927 + 104 - - Toxin
L1O95_RS10865 2203059..2204135 - 1077 WP_063103093.1 phage integrase Arm DNA-binding domain-containing protein -
L1O95_RS10870 2204101..2204382 - 282 WP_137689817.1 excisionase -
L1O95_RS10875 2204489..2204677 - 189 WP_001356607.1 DUF1187 family protein -
- 2204493..2204671 + 179 NuclAT_0 - -
- 2204493..2204671 + 179 NuclAT_0 - -
- 2204493..2204671 + 179 NuclAT_0 - -
- 2204493..2204671 + 179 NuclAT_0 - -
L1O95_RS10880 2204670..2204864 - 195 WP_021500490.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
L1O95_RS10885 2204928..2205980 - 1053 WP_001004422.1 RecT family recombinase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2195284..2268348 73064


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T232368 NZ_CP091020:2202824-2202927 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT232368 NZ_CP091020:c2202928-2202694 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References