Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2202698..2202932 Replicon chromosome
Accession NZ_CP091018
Organism Escherichia coli strain STEC307

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2202828..2202931 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2202698..2202932 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L1O94_RS10830 2199253..2199915 - 663 WP_000944256.1 exodeoxyribonuclease X -
L1O94_RS10835 2199939..2200595 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
L1O94_RS10840 2200697..2200927 - 231 WP_000916763.1 DNA polymerase III subunit theta -
L1O94_RS10845 2201066..2201440 + 375 WP_000204699.1 CopC domain-containing protein YobA -
L1O94_RS10850 2201444..2202316 + 873 WP_033813010.1 copper homeostasis membrane protein CopD -
L1O94_RS10855 2202329..2202670 + 342 WP_000976492.1 YebY family protein -
- 2202698..2202932 - 235 - - Antitoxin
- 2202828..2202931 + 104 - - Toxin
L1O94_RS10860 2203063..2204139 - 1077 WP_063103093.1 phage integrase Arm DNA-binding domain-containing protein -
L1O94_RS10865 2204105..2204386 - 282 WP_137689817.1 excisionase -
L1O94_RS10870 2204493..2204681 - 189 WP_001356607.1 DUF1187 family protein -
- 2204497..2204675 + 179 NuclAT_0 - -
- 2204497..2204675 + 179 NuclAT_0 - -
- 2204497..2204675 + 179 NuclAT_0 - -
- 2204497..2204675 + 179 NuclAT_0 - -
L1O94_RS10875 2204674..2204868 - 195 WP_021500490.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
L1O94_RS10880 2204932..2205984 - 1053 WP_001004422.1 RecT family recombinase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2197196..2258070 60874


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T232340 NZ_CP091018:2202828-2202931 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT232340 NZ_CP091018:c2202932-2202698 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References