Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2202688..2202922 Replicon chromosome
Accession NZ_CP091016
Organism Escherichia coli strain STEC306

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2202818..2202921 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2202688..2202922 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L1O96_RS10835 2199243..2199905 - 663 WP_000944256.1 exodeoxyribonuclease X -
L1O96_RS10840 2199929..2200585 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
L1O96_RS10845 2200687..2200917 - 231 WP_000916763.1 DNA polymerase III subunit theta -
L1O96_RS10850 2201056..2201430 + 375 WP_000204699.1 CopC domain-containing protein YobA -
L1O96_RS10855 2201434..2202306 + 873 WP_033813010.1 copper homeostasis membrane protein CopD -
L1O96_RS10860 2202319..2202660 + 342 WP_000976492.1 YebY family protein -
- 2202688..2202922 - 235 - - Antitoxin
- 2202818..2202921 + 104 - - Toxin
L1O96_RS10865 2203053..2204129 - 1077 WP_063103093.1 phage integrase Arm DNA-binding domain-containing protein -
L1O96_RS10870 2204095..2204376 - 282 WP_137689817.1 excisionase -
L1O96_RS10875 2204483..2204671 - 189 WP_001356607.1 DUF1187 family protein -
- 2204487..2204665 + 179 NuclAT_0 - -
- 2204487..2204665 + 179 NuclAT_0 - -
- 2204487..2204665 + 179 NuclAT_0 - -
- 2204487..2204665 + 179 NuclAT_0 - -
L1O96_RS10880 2204664..2204858 - 195 WP_021500490.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
L1O96_RS10885 2204922..2205974 - 1053 WP_001004422.1 RecT family recombinase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2197186..2258060 60874


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T232312 NZ_CP091016:2202818-2202921 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT232312 NZ_CP091016:c2202922-2202688 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References