Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 12015..12550 Replicon plasmid unnamed2
Accession NZ_CP090964
Organism Edwardsiella piscicida strain CZ12001

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag L1P06_RS18085 Protein ID WP_109609915.1
Coordinates 12015..12302 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag L1P06_RS18090 Protein ID WP_236893559.1
Coordinates 12299..12550 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L1P06_RS18070 (L1P06_18070) 8942..9958 - 1017 WP_236893552.1 DsbC family protein -
L1P06_RS18075 (L1P06_18075) 9962..11233 - 1272 WP_236893554.1 conjugal transfer protein TrbA -
L1P06_RS18080 (L1P06_18080) 11317..11997 - 681 WP_236893556.1 plasmid IncI1-type surface exclusion protein ExcA -
L1P06_RS18085 (L1P06_18085) 12015..12302 - 288 WP_109609915.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
L1P06_RS18090 (L1P06_18090) 12299..12550 - 252 WP_236893559.1 antitoxin Antitoxin
L1P06_RS18095 (L1P06_18095) 12641..14788 - 2148 WP_236893560.1 DotA/TraY family protein -
L1P06_RS18100 (L1P06_18100) 14843..15361 - 519 WP_236893561.1 conjugal transfer protein TraX -
L1P06_RS18105 (L1P06_18105) 15358..16554 - 1197 WP_236893562.1 conjugal transfer protein TraW -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid tet(A) - 1..89974 89974


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11110.03 Da        Isoelectric Point: 10.9979

>T232236 WP_109609915.1 NZ_CP090964:c12302-12015 [Edwardsiella piscicida]
MTYRVKFRSDALKEWNNLDKAIQQQFARKLKKCAENPHNPSARLRGMPNCYKIKLRASGFRLVYQVINDELIIAVVAVGK
RERSEVYTLASKRLR

Download         Length: 288 bp

>T232236 NZ_CP127274:c3094457-3094101 [Mycobacterium tuberculosis]
GTGATGCGCCGCGGTGAGATTTGGCAGGTCGATCTCGACCCCGCTCGAGGTAGCGAAGCGAACAACCAGCGCCCCGCCGT
CGTCGTCAGCAACGACCGGGCCAACGCGACCGCCACGCGTCTTGGGCGCGGCGTCATCACCGTCGTGCCGGTGACGAGCA
ACATCGCCAAGGTCTATCCGTTTCAGGTGTTGTTGTCGGCCACCACTACTGGTCTCCAGGTCGACTGCAAGGCGCAGGCC
GAGCAAATCAGATCGATTGCTACCGAGCGGTTGCTCCGGCCAATCGGCCGAGTTTCAGCCGCCGAACTTGCCCAGCTCGA
TGAGGCTTTGAAACTGCATCTCGACTTATGGTCGTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9366.57 Da        Isoelectric Point: 4.6436

>AT232236 WP_236893559.1 NZ_CP090964:c12550-12299 [Edwardsiella piscicida]
MPNIIHSDTTASVSELKKNPMATVNSGAGFPVAILNHNQPVFYCIPAELYEQMLDYIDDQELSKQVQKRSKQTLHDVDLD
SYL

Download         Length: 252 bp

>AT232236 NZ_CP127274:c3094671-3094441 [Mycobacterium tuberculosis]
GTGAAGTTGAGCGTGAGCCTGTCCGATGACGACGTCGCGATCCTGGACGCATATGTGAAACGAGCGGGATTACCATCCCG
CTCCGCCGGCCTGCAGCATGCGATCCGCGTGCTTCGCTACCCCACGCTCGAAGATGACTATGCCAACGCATGGCAAGAAT
GGTCGGCAGCCGGCGACACGGACGCGTGGGAGCAGACCGTCGGCGACGGAGTCGGTGATGCGCCGCGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References