Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Xre(antitoxin)
Location 1295866..1296995 Replicon chromosome
Accession NZ_CP090959
Organism Simiduia sp. 21SJ11W-1

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag L1F30_RS05790 Protein ID WP_253360574.1
Coordinates 1296237..1296995 (+) Length 253 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag L1F30_RS05785 Protein ID WP_253360572.1
Coordinates 1295866..1296237 (+) Length 124 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L1F30_RS05770 (L1F30_05770) 1291021..1292250 + 1230 WP_253360562.1 glycosyltransferase family 9 protein -
L1F30_RS05775 (L1F30_05775) 1292431..1293993 + 1563 WP_253360568.1 SulP family inorganic anion transporter -
L1F30_RS05780 (L1F30_05780) 1294494..1295780 + 1287 WP_253360570.1 M20/M25/M40 family metallo-hydrolase -
L1F30_RS05785 (L1F30_05785) 1295866..1296237 + 372 WP_253360572.1 MbcA/ParS/Xre antitoxin family protein Antitoxin
L1F30_RS05790 (L1F30_05790) 1296237..1296995 + 759 WP_253360574.1 RES family NAD+ phosphorylase Toxin
L1F30_RS05795 (L1F30_05795) 1297284..1297634 - 351 WP_253360576.1 hypothetical protein -
L1F30_RS05800 (L1F30_05800) 1297721..1298230 - 510 WP_253360578.1 YfiR/HmsC family protein -
L1F30_RS05805 (L1F30_05805) 1298232..1300574 - 2343 WP_253360580.1 TonB-dependent receptor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(61-203)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(73-121)


Sequences

Toxin        


Download         Length: 253 a.a.        Molecular weight: 27791.51 Da        Isoelectric Point: 5.6195

>T232221 WP_253360574.1 NZ_CP090959:1296237-1296995 [Simiduia sp. 21SJ11W-1]
MALWASLDGQQAIGPLTLELVRVVESQEEIATLSLVDSMAEQDILESLLEDSKPGQLPGNLHYLLASPFRYPPLQWGSRF
GRTHEPSLFYGSLNIETALTECAFYRFVFLSGVTAPFPKAVVSQHTSFRVRGHGERGVNLTLPPFAEHTDALRSPEDYRA
AQALGSDMREAGVQVVIYLSARDRRASALNGAVFDPQVFAKSQPQRFQAWTCHATTEAVRFIAAPGATPGREIFAFTRED
FLVDGRLPMPPA

Download         Length: 759 bp

>T232221 NZ_CP127274:c2217233-2216673 [Mycobacterium tuberculosis]
GTGAGCGATGCCCTCGATGAAGGGCTCGTCCAGCGTATCGACGCACGCGGAACAATTGAGTGGTCGGAAACGTGCTACCG
GTATACCGGCGCGCACCGTGACGCCTTGTCCGGTGAGGGCGCGCGCAGATTCGGAGGCAGGTGGAATCCGCCGCTGCTCT
TTCCGGCGATCTATCTTGCTGATTCCGCCCAAGCCTGCATGGTTGAGGTGGAACGGGCGGCGCAAGCGGCTTCAACGACC
GCAGAGAAGATGCTCGAGGCGGCCTACCGACTACACACGATCGACGTCACGGACCTGGCCGTCCTCGATCTGACAACCCC
GCAAGCTCGGGAAGCCGTGGGGCTCGAGAACGACGACATCTATGGCGACGACTGGTCAGGGTGCCAGGCGGTCGGACATG
CGGCCTGGTTCTTGCACATGCAAGGTGTCCTCGTGCCGGCGGCGGGCGGTGTCGGCCTCGTTGTCACCGCGTATGAACAG
CGAACTCGGCCGGGCCAACTACAACTGCGACAAAGCGTCGATCTGACGCCTGCTCTTTACCAAGAACTTCGAGCCACGTA
G

Antitoxin


Download         Length: 124 a.a.        Molecular weight: 13450.53 Da        Isoelectric Point: 10.2231

>AT232221 WP_253360572.1 NZ_CP090959:1295866-1296237 [Simiduia sp. 21SJ11W-1]
MSALQMNQPEAAAVLCKALQNTQQAFGLTNEELGRIIGKDRSTIGRMFDKGQLSPGSKEGELALLLVRVYRSLFALLGGS
QSQMQHWLNTANSHLQATPRSMMSSVQGLVNLVTYLDAMRGRV

Download         Length: 372 bp

>AT232221 NZ_CP127274:c2217571-2217230 [Mycobacterium tuberculosis]
ATGGGAGTAAATGTGCTCGCCTCGACCGTGTCGGGTGCGATCGAGCGCTTGGGATTGACCTACGAGGAAGTCGGTGACAT
CGTCGATGCCTCGCCGCGTTCCGTGGCGCGATGGACCGCAGGTCAGGTGGTTCCCCAACGCCTCAACAAGCAACGACTTA
TCGAGCTGGCCTATGTCGCCGACGCCCTCGCGGAAGTGCTGCCGCGTGACCAGGCGAACGTGTGGATGTTTTCGCCGAAT
CGGTTACTGGAACACCGCAAGCCTGCCGACCTCGTGCGAGACGGCGAGTACCAACGCGTGTTGGCGCTCATCGACGCGAT
GGCGGAGGGAGTGTTCGTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References