Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4717527..4717896 Replicon chromosome
Accession NZ_CP090954
Organism Xanthomonas arboricola pv. pruni strain Xcp1

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0B2CMD0
Locus tag L1B16_RS20335 Protein ID WP_016904515.1
Coordinates 4717527..4717661 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID V7Z8F2
Locus tag L1B16_RS20340 Protein ID WP_006451340.1
Coordinates 4717744..4717896 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L1B16_RS20320 (L1B16_08980) 4714594..4715538 - 945 WP_039512622.1 MBL fold metallo-hydrolase -
L1B16_RS20325 (L1B16_08985) 4715596..4716885 - 1290 WP_039814994.1 tryptophan--tRNA ligase -
L1B16_RS20330 (L1B16_08990) 4717067..4717276 - 210 WP_039512625.1 CsbD family protein -
L1B16_RS20335 (L1B16_08995) 4717527..4717661 - 135 WP_016904515.1 entericidin A/B family lipoprotein Toxin
L1B16_RS20340 (L1B16_09000) 4717744..4717896 - 153 WP_006451340.1 entericidin A/B family lipoprotein Antitoxin
L1B16_RS20345 (L1B16_09005) 4718006..4718929 - 924 WP_039512664.1 arginase -
L1B16_RS20350 (L1B16_09010) 4719405..4719857 + 453 WP_039512628.1 roadblock/LC7 domain-containing protein -
L1B16_RS20355 (L1B16_09015) 4719921..4720280 + 360 WP_039512630.1 hypothetical protein -
L1B16_RS20360 (L1B16_09020) 4720374..4721291 + 918 WP_039512632.1 hypothetical protein -
L1B16_RS20365 (L1B16_09025) 4721288..4721830 + 543 WP_016904520.1 GTPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4443.26 Da        Isoelectric Point: 9.3487

>T232219 WP_016904515.1 NZ_CP090954:c4717661-4717527 [Xanthomonas arboricola pv. pruni]
MKRAIVLLVLSVLSVGMLSGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T232219 NZ_CP127274:c2187911-2187615 [Mycobacterium tuberculosis]
GTGAGTAGCCGATACCTTCTCTCGCCTGCCGCGCAGGCACATCTGGAAGAGATCTGGGACTGCACCTATGACCGTTGGGG
TGTCGATCAGGCCGAGCAGTACCTGCGCGAACTTCAACACGCTATCGACCGTGCTGCGGCAAACCCGCGGATCGGACGAG
CGTGCGACGAGATTCGCCCCGGCTATCGCAAGCTCTCGGCCGGGTCACACACGTTGTTCTATCGGGTGACTGGCGAAGGC
ACCATCGACGTCGTGCGAGTCCTGCACCAACGGATGGACGTCGACCGGAACCTCTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5168.11 Da        Isoelectric Point: 8.2782

>AT232219 WP_006451340.1 NZ_CP090954:c4717896-4717744 [Xanthomonas arboricola pv. pruni]
MKRLLTLMVLGLFSAGVMTGCNTMAGAGKDMQGAGEKVEKKADNCSDGKC

Download         Length: 153 bp

>AT232219 NZ_CP127274:c2188159-2187908 [Mycobacterium tuberculosis]
GTGGGTAAGAACACGTCCTTCGTCCTCGACGAGCACTACAGCGCCTTCATCGACGGCGAGATCGCCGCGGGCCGCTACCG
GTCGGCCAGTGAAGTCATCCGCTCCGCGTTGCGACTGCTCGAGGACCGTGAAACCCAGCTGCGCGCGCTTCGTGAGGCTC
TCGAGGCCGGCGAACGCAGCGGCAGCTCGACACCGTTCGACTTCGACGGATTCCTCGGTCGTAAGCGGGCTGACGCCTCG
CGTGGCCGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0B2CMD0

Antitoxin

Source ID Structure
AlphaFold DB A0A2N7V051

References