Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1943842..1943987 Replicon chromosome
Accession NZ_CP090931
Organism Klebsiella pneumoniae strain ONE259

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1943878..1943980 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1943842..1943987 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I7858_RS09430 (I7858_09430) 1938972..1941032 + 2061 WP_004151449.1 oligopeptidase B -
I7858_RS09435 (I7858_09435) 1941036..1941695 - 660 WP_032425085.1 exodeoxyribonuclease X -
I7858_RS09440 (I7858_09440) 1941774..1942004 - 231 WP_002911406.1 DNA polymerase III subunit theta -
I7858_RS09445 (I7858_09445) 1942117..1942491 + 375 WP_004151448.1 CopC domain-containing protein YobA -
I7858_RS09450 (I7858_09450) 1942495..1943364 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
I7858_RS09455 (I7858_09455) 1943381..1943719 + 339 WP_016529031.1 YebY family protein -
- 1943842..1943987 - 146 - - Antitoxin
- 1943878..1943980 + 103 - - Toxin
I7858_RS09460 (I7858_09460) 1944355..1944498 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
I7858_RS09465 (I7858_09465) 1944603..1945571 - 969 WP_004151446.1 VirK/YbjX family protein -
I7858_RS09470 (I7858_09470) 1945728..1946381 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
I7858_RS09475 (I7858_09475) 1946378..1946569 - 192 WP_002911395.1 YebW family protein -
I7858_RS09480 (I7858_09480) 1946667..1946906 - 240 WP_002911393.1 YebV family protein -
I7858_RS09485 (I7858_09485) 1947022..1948455 - 1434 WP_032411854.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T232191 NZ_CP090931:1943878-1943980 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT232191 NZ_CP090931:c1943987-1943842 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References