Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 998990..999663 Replicon chromosome
Accession NZ_CP090898
Organism Synechococcus sp. NB0720_010

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LY254_RS05310 Protein ID WP_247479406.1
Coordinates 999229..999663 (+) Length 145 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LY254_RS05305 Protein ID WP_247479405.1
Coordinates 998990..999229 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LY254_RS05285 (LY254_05285) 994462..996528 + 2067 WP_247479401.1 PBP1A family penicillin-binding protein -
LY254_RS05290 (LY254_05290) 996525..997850 - 1326 WP_247479402.1 16S rRNA (cytosine(967)-C(5))-methyltransferase -
LY254_RS05295 (LY254_05295) 997847..998179 - 333 WP_247479403.1 MGMT family protein -
LY254_RS05300 (LY254_05300) 998230..998925 + 696 WP_247479404.1 tRNA (guanosine(18)-2'-O)-methyltransferase TrmH -
LY254_RS05305 (LY254_05305) 998990..999229 + 240 WP_247479405.1 CopG family transcriptional regulator Antitoxin
LY254_RS05310 (LY254_05310) 999229..999663 + 435 WP_247479406.1 PIN domain-containing protein Toxin
LY254_RS05315 (LY254_05315) 999666..1000535 - 870 WP_247479407.1 ABC transporter permease -
LY254_RS05320 (LY254_05320) 1000683..1000802 + 120 Protein_1047 prepilin-type N-terminal cleavage/methylation domain-containing protein -
LY254_RS05325 (LY254_05325) 1001214..1001555 + 342 WP_247479408.1 hypothetical protein -
LY254_RS05330 (LY254_05330) 1001623..1003080 + 1458 WP_247479410.1 hypothetical protein -
LY254_RS05335 (LY254_05335) 1003106..1003825 + 720 WP_247479413.1 peptidylprolyl isomerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain toxin

(5-130)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 145 a.a.        Molecular weight: 15852.06 Da        Isoelectric Point: 6.5648

>T232080 WP_247479406.1 NZ_CP090898:999229-999663 [Synechococcus sp. NB0720_010]
MRHTTALLDVNVLIALLDPHHVHHELCHGWFADRGAAPWASCAMTQNAVLRILGNPRYPNSPGPPPTIAPHLDSLVEHPG
HEFWDSNPSLLSQGFIARSALIDYAQITDLYLLALARHHGGTLATLDQRIKVDGSQEALELIRP

Download         Length: 435 bp

>T232080 NZ_CP090898:999229-999663 [Synechococcus sp. NB0720_010]
ATGCGACACACCACAGCCCTCCTCGACGTCAATGTCTTAATCGCGCTACTGGATCCGCACCACGTTCACCACGAGCTCTG
TCATGGCTGGTTCGCGGACCGTGGTGCCGCCCCATGGGCCAGCTGCGCGATGACGCAAAACGCTGTCCTGCGCATCCTTG
GCAATCCGCGCTACCCCAACTCCCCCGGGCCGCCGCCAACCATTGCGCCGCACCTCGACAGCTTGGTGGAACACCCAGGG
CATGAGTTCTGGGACAGCAATCCCAGCCTGCTGAGCCAAGGGTTCATCGCCCGTTCCGCCCTGATCGATTACGCCCAGAT
CACAGATCTCTATCTGCTGGCACTGGCCAGACACCACGGTGGAACGCTGGCGACCTTGGACCAGCGCATCAAGGTGGACG
GCAGCCAAGAGGCACTGGAGCTCATCCGCCCGTAG

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8765.08 Da        Isoelectric Point: 10.4472

>AT232080 WP_247479405.1 NZ_CP090898:998990-999229 [Synechococcus sp. NB0720_010]
MRTTLSLDDDVLAAAKVLARQRKQPIGSVISELARQGLAQANRQNPEPAHIKRNGLMLIPRRLDGSPVDLELVNNLRED

Download         Length: 240 bp

>AT232080 NZ_CP090898:998990-999229 [Synechococcus sp. NB0720_010]
ATGCGCACGACCCTGTCGCTCGATGACGACGTCCTCGCTGCCGCCAAGGTCCTGGCGCGGCAGCGCAAACAACCCATTGG
CAGCGTCATCAGCGAACTGGCTCGCCAGGGATTGGCGCAAGCCAACCGGCAGAACCCAGAGCCCGCCCACATCAAGCGCA
ATGGGCTGATGCTGATTCCACGCCGCCTGGATGGATCACCGGTGGACCTTGAGCTGGTGAACAACCTGCGGGAGGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References