Detailed information of TA system TA232078

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-yefM/YoeB-RelB
• Location: 728473..728992
• Replicon: chromosome
• Accession: NZ_CP090898
• Organism: Synechococcus sp. NB0720_010

Toxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: LY254_RS03970
• Protein ID: WP_247479051.1
• Coordinates: 728720..728992 (+)
• Length: 91 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: LY254_RS03965
• Protein ID: WP_247479049.1
• Coordinates: 728473..728733 (+)
• Length: 87 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LY254_RS03930 (LY254_03930)	723737..724747	-	1011	WP_247479045.1	lycopene cyclase family protein	-
LY254_RS03935 (LY254_03935)	724752..725315	-	564	WP_010317848.1	photosystem II oxygen evolving complex protein PsbP	-
LY254_RS03940 (LY254_03940)	725432..726001	+	570	WP_029626389.1	recombination mediator RecR	-
LY254_RS03945 (LY254_03945)	726006..726911	+	906	WP_247479725.1	lipoyl synthase	-
LY254_RS03950 (LY254_03950)	726908..727279	-	372	WP_247479046.1	DUF1622 domain-containing protein	-
LY254_RS03955 (LY254_03955)	727289..727936	-	648	WP_247479047.1	DUF429 domain-containing protein	-
LY254_RS03960 (LY254_03960)	727933..728427	-	495	WP_247479048.1	hypothetical protein	-
LY254_RS03965 (LY254_03965)	728473..728733	+	261	WP_247479049.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
LY254_RS03970 (LY254_03970)	728720..728992	+	273	WP_247479051.1	Txe/YoeB family addiction module toxin	Toxin
LY254_RS03975 (LY254_03975)	728980..729927	-	948	WP_247479056.1	DUF952 domain-containing protein	-
LY254_RS03980 (LY254_03980)	729933..730847	-	915	WP_247479057.1	rhodanese-related sulfurtransferase	-
LY254_RS03985 (LY254_03985)	730844..731746	-	903	WP_247479726.1	biotin synthase BioB	-
LY254_RS03990 (LY254_03990)	731826..732620	-	795	WP_247479059.1	isoprenyl transferase	-
LY254_RS03995 (LY254_03995)	732617..733384	-	768	WP_247479727.1	diadenylate cyclase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (9-88)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 91 a.a.
• Molecular weight: 10683.35 Da
• Isoelectric Point: 9.5635

>T232078 WP_247479051.1 NZ_CP090898:728720-728992 [Synechococcus sp. NB0720_010]
MPSLERLSWTTAAWGDYLYWQGQDRKTLRRINQLIQACLRHPFEGIGKPEPLRESLSGCWSRRIDAEHRLVYRVDGPLLV
ILACRYHYRV

Nucleotide

• Length: 273 bp

>T232078 NZ_CP127244:c3423346-3423044 [Salinicola sp. JS01]
GTGGCTGAGCTCCTCTGGTCCCAGCCGTCGCTACAGGCGCTCGACGAGATCGCCGAGTATATTGCGCTGGACAATCCTGC
TGCTGCCCGGGCGCTGGTCGCAAGGGTGCTCAGGGCGGTCGAGAGGTTGGTCGAGTTCCCGGCCTCCGGGCGCCAGCCGC
CGGAGTTGCCGGGCTCCGGTTATCGCGAAGTGGTGGTGCCACCCTGTCGGGTGTTCTATCGCCAGGAGGGCGAACGGATA
TTGATCGTTCATCTCATGCGTGAAGAGCGTGCGCTACGCCGCTATATGCTCGATCCCGAGTGA

Antitoxin

Protein

• Length: 87 a.a.
• Molecular weight: 9480.62 Da
• Isoelectric Point: 4.4193

>AT232078 WP_247479049.1 NZ_CP090898:728473-728733 [Synechococcus sp. NB0720_010]
MQVVSFSEARQSFKAVLDRVEADADVTLITRRDASSAVLMSLETYNSLMETVHLLRSPANAAHLQQSLEQADRGELVDHA
LIDAEP

Nucleotide

• Length: 261 bp

>AT232078 NZ_CP127244:c3423613-3423359 [Salinicola sp. JS01]
ATGAAAGTCGAGCTGGTAACCAACCTCAAGCGCCGTGCGACGCAGATTCTTGGCGAGCTGCGTGTGTCGAAAGAGCCCGT
GATGATTACCGAGCACGGCAGGCCTTCCGCCTATCTGGTGGATATCGACGACTACGAGTTCATGCAGCGGCGCCTGGCAC
TCCTCGAGGGCCTTTCGCGCGGTGAGCGTGCGCTGCAGGAGGGACGTTCTCTGGATCATCAGGCGGCGCGCGGGTCCCTG
AGCAGATGGCTCTAG