Detailed information of TA system TA232076

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 2800451..2801090
• Replicon: chromosome
• Accession: NZ_CP090890
• Organism: Acinetobacter junii strain WCO-9

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: L0U97_RS13145
• Protein ID: WP_234856505.1
• Coordinates: 2800451..2800846 (-)
• Length: 132 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: A0A365PHJ6
• Locus tag: L0U97_RS13150
• Protein ID: WP_039047469.1
• Coordinates: 2800833..2801090 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L0U97_RS13125	2795568..2797778	-	2211	WP_234856504.1	TRAP transporter large permease subunit	-
L0U97_RS13130	2797932..2798501	-	570	WP_004951830.1	rhombosortase	-
L0U97_RS13135	2798590..2799672	-	1083	WP_099948048.1	hypothetical protein	-
L0U97_RS13140	2800033..2800239	-	207	WP_171053826.1	hypothetical protein	-
L0U97_RS13145	2800451..2800846	-	396	WP_234856505.1	hypothetical protein	Toxin
L0U97_RS13150	2800833..2801090	-	258	WP_039047469.1	succinate dehydrogenase assembly factor 2	Antitoxin
L0U97_RS13155	2801275..2802447	+	1173	WP_004909327.1	acyl-CoA dehydrogenase family protein	-
L0U97_RS13160	2802495..2802995	-	501	WP_234856506.1	DUF2059 domain-containing protein	-
L0U97_RS13165	2803116..2804606	-	1491	WP_004909331.1	NAD(P)/FAD-dependent oxidoreductase	-
L0U97_RS13170	2804981..2805532	+	552	WP_234856507.1	hypothetical protein	-
L0U97_RS13175	2805646..2806011	-	366	WP_004641032.1	50S ribosomal protein L17	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 132 a.a.
• Molecular weight: 15437.31 Da
• Isoelectric Point: 8.2489

>T232076 WP_234856505.1 NZ_CP090890:c2800846-2800451 [Acinetobacter junii]
MYTAKRIFELQSSRFSLGLQLFCFLGINILLYQLLSAFLWLVCLLIMGWAGWSALNKPKINQIEYLYDDDWSIRFDGAVP
NIEQGKLLKIVDHHLYIVLYFSNIESKTCVIWWDQLSLNQWKMLKLLSKLA

Nucleotide

• Length: 396 bp

>T232076 NZ_CP127244:c238374-238186 [Salinicola sp. JS01]
ATGAAAAGCGCGGACGTGATCAAACGGTTGGAAGCCGAAGGCTGGCATCACGTCGGCGGCAAAGGCGATCATATGAAATT
CAAACACCCTGACAAGCCGGTTCACGTCGTTGTCCCGCACCCGCGCAAGGATCTCGCCACCGGCACGCTGCGCAACATCT
ATCGTCAAGCCGGCTGGATCTGGAGGTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10116.64 Da
• Isoelectric Point: 4.5732

>AT232076 WP_039047469.1 NZ_CP090890:c2801090-2800833 [Acinetobacter junii]
MSDEMTLEERKVIYRARRGLKEIDVYFDPYVKQYYLTADPTEKALFAELVDQEDPDLLDWFMEVGEPPRAELKAFILKLK
KYVHG

Nucleotide

• Length: 258 bp

>AT232076 NZ_CP127244:c238182-237790 [Salinicola sp. JS01]
ATGCTCTACCCCGCCTACATTCACAAGGATCGCGACAGCGCCTACGGCGTGACCTTTCCCGACTTCCCCGGCTGCTTCTC
GGCCGCGGACGAACTCTCAGAGCTACCGCGTCTGGCTCAAGAAGCGGTCGAGGTCTACTTCGACGGCGAAGACATGGCCA
TCCCGCCCCCGTCGACGCCGGAAACCTGGGCGGACCATGCGGATTTTCAGGATGGCTACTGGATGCTGATCGATATCGAT
CTGTCCAAGCTCAGTCACCGCGCCGTGCGCGTCAATATCAGCCTGCCCGAGTCGCTGGTGGCCAAGATCGATCACGCAGC
CAAAGCGCGCCACCTCAGCCGCTCCGCCTTTCTGGCCATGGCGGCTCAGCATGAGATGAGCGAGCCGCGCTGA

Structures

Antitoxin

• AlphaFold DB: A0A365PHJ6