Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | TsaAT/- |
| Location | 1439121..1439598 | Replicon | chromosome |
| Accession | NZ_CP090876 | ||
| Organism | Staphylococcus aureus strain SAUR_BFS12 | ||
Toxin (Protein)
| Gene name | TsaT | Uniprot ID | T1Y7S2 |
| Locus tag | L0998_RS07225 | Protein ID | WP_000052076.1 |
| Coordinates | 1439410..1439598 (+) | Length | 63 a.a. |
Antitoxin (Protein)
| Gene name | TsaA | Uniprot ID | - |
| Locus tag | L0998_RS07220 | Protein ID | WP_001059689.1 |
| Coordinates | 1439121..1439381 (+) | Length | 87 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| L0998_RS07185 (1434514) | 1434514..1435230 | - | 717 | WP_054189299.1 | type I 3-dehydroquinate dehydratase | - |
| L0998_RS07190 (1435378) | 1435378..1435800 | + | 423 | WP_000974455.1 | organic hydroperoxide resistance protein | - |
| L0998_RS07195 (1436199) | 1436199..1436693 | + | 495 | WP_054189298.1 | GNAT family N-acetyltransferase | - |
| L0998_RS07200 (1436849) | 1436849..1437466 | + | 618 | WP_054189297.1 | LysE/ArgO family amino acid transporter | - |
| L0998_RS07205 (1437539) | 1437539..1438120 | - | 582 | WP_054189296.1 | histidine phosphatase family protein | - |
| L0998_RS07210 (1438344) | 1438344..1438580 | + | 237 | WP_000368687.1 | hypothetical protein | - |
| L0998_RS07215 (1438577) | 1438577..1438780 | - | 204 | WP_000145163.1 | sterile alpha motif-like domain-containing protein | - |
| L0998_RS07220 (1439121) | 1439121..1439381 | + | 261 | WP_001059689.1 | hypothetical protein | Antitoxin |
| L0998_RS07225 (1439410) | 1439410..1439598 | + | 189 | WP_000052076.1 | hypothetical protein | Toxin |
| L0998_RS07230 (1439787) | 1439787..1440356 | + | 570 | WP_054189295.1 | lipoprotein N-acylation protein LnsA | - |
| L0998_RS07235 (1440444) | 1440444..1440728 | + | 285 | WP_054189294.1 | hypothetical protein | - |
| L0998_RS07240 (1440790) | 1440790..1441008 | + | 219 | WP_054189293.1 | hypothetical protein | - |
| L0998_RS07245 (1441506) | 1441506..1441706 | - | 201 | WP_001059082.1 | cold-shock protein | - |
| L0998_RS07250 (1442063) | 1442063..1442749 | - | 687 | WP_054189292.1 | thermonuclease family protein | - |
| L0998_RS07255 (1443091) | 1443091..1443648 | - | 558 | WP_054189291.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 63 a.a. Molecular weight: 7142.82 Da Isoelectric Point: 9.9971
>T231998 WP_000052076.1 NZ_CP090876:1439410-1439598 [Staphylococcus aureus]
MSLHFAILFWLALIFLVAATFILVLMKKTGKESKKESYLSFTVILYIFGFAILIYTFIFGVL
MSLHFAILFWLALIFLVAATFILVLMKKTGKESKKESYLSFTVILYIFGFAILIYTFIFGVL
Download Length: 189 bp
>T231998 NZ_CP127153:740977-741462 [Klebsiella pneumoniae subsp. pneumoniae]
ATGATCTCGGCACCAGAACCGCTTCATGCCGGGCATATTCTTACCCCGTTTTGCTGCGGTATAGATTCCATGGATCACTG
GCTGAAACAGCGGGCGATGAAAAATCAGGTTACTGGCGCATCCCGCACCTTTGTCTGCTGCGACGACGCGAAGGTGATGG
CTTACTACTCACTGGCTTCCAGCGCTGTGACGACAAATACTGCGCCGGGTCGTTTTCGCCGCAATATGCCTGCCCCGATC
CCGGTTGTGGTACTGGGTCGTCTGGCGGTGGATAAATCACTACATGGGAAAGGTGTCGGGCGGGCCCTGGTACGTGATGC
CGGGCTGCGTGTGATTCAGGTGGCGGAGACTATCGGCATTCGCGGGATGCTGGTTCACGCCCTGTCGGATGAAGCACGGG
ATTTTTACCTGCGGGTGGGGTTTGAGCCGTCGCCGATGGATCCGATGATGTTGATGGTGACGTTGAGGGATTTGGTTAAT
GCCTGA
ATGATCTCGGCACCAGAACCGCTTCATGCCGGGCATATTCTTACCCCGTTTTGCTGCGGTATAGATTCCATGGATCACTG
GCTGAAACAGCGGGCGATGAAAAATCAGGTTACTGGCGCATCCCGCACCTTTGTCTGCTGCGACGACGCGAAGGTGATGG
CTTACTACTCACTGGCTTCCAGCGCTGTGACGACAAATACTGCGCCGGGTCGTTTTCGCCGCAATATGCCTGCCCCGATC
CCGGTTGTGGTACTGGGTCGTCTGGCGGTGGATAAATCACTACATGGGAAAGGTGTCGGGCGGGCCCTGGTACGTGATGC
CGGGCTGCGTGTGATTCAGGTGGCGGAGACTATCGGCATTCGCGGGATGCTGGTTCACGCCCTGTCGGATGAAGCACGGG
ATTTTTACCTGCGGGTGGGGTTTGAGCCGTCGCCGATGGATCCGATGATGTTGATGGTGACGTTGAGGGATTTGGTTAAT
GCCTGA
Antitoxin
Download Length: 87 a.a. Molecular weight: 10009.20 Da Isoelectric Point: 4.4986
>AT231998 WP_001059689.1 NZ_CP090876:1439121-1439381 [Staphylococcus aureus]
MNNILLNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICGVILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPI
FYRFIG
MNNILLNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICGVILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPI
FYRFIG
Download Length: 261 bp
>AT231998 NZ_CP127153:740687-740980 [Klebsiella pneumoniae subsp. pneumoniae]
ATGCCAGCCGCAAACAGCATGTCCATAAAACGCGAAACGTTAAATCTGCGCATTAAACCTGCCGAACGCGATCTTATTGA
TCGGGCGGCGAAAGCCAGAGGGAAAAACCGCACAGACTTTGTGCTGGAGGCCGCCCGCGCTGCCGCTGAGGAAGCGCTGA
TTGAGCAACGCATCATTATGGCCGATCCGCAGGCTTATCAGGAATTTCTCGCTCGTCTGGATCAGGCTCCTGCACCTAAT
GCCGCACTGCGTAAAACTATGCAGACCCCTGCGCCGTGGGAACAGGAAGAATGA
ATGCCAGCCGCAAACAGCATGTCCATAAAACGCGAAACGTTAAATCTGCGCATTAAACCTGCCGAACGCGATCTTATTGA
TCGGGCGGCGAAAGCCAGAGGGAAAAACCGCACAGACTTTGTGCTGGAGGCCGCCCGCGCTGCCGCTGAGGAAGCGCTGA
TTGAGCAACGCATCATTATGGCCGATCCGCAGGCTTATCAGGAATTTCTCGCTCGTCTGGATCAGGCTCCTGCACCTAAT
GCCGCACTGCGTAAAACTATGCAGACCCCTGCGCCGTGGGAACAGGAAGAATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|