Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 456831..457472 Replicon chromosome
Accession NZ_CP090788
Organism Burkholderia vietnamiensis strain 2003Ycf867

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag L0Y95_RS21735 Protein ID WP_249472954.1
Coordinates 457134..457472 (-) Length 113 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag L0Y95_RS21730 Protein ID WP_011881499.1
Coordinates 456831..457130 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0Y95_RS21705 (L0Y95_21705) 451938..453209 + 1272 WP_014724582.1 anthranilate 1,2-dioxygenase large subunit AndAc -
L0Y95_RS21710 (L0Y95_21710) 453227..453712 + 486 WP_034194948.1 anthranilate 1,2-dioxygenase small subunit AndAd -
L0Y95_RS21715 (L0Y95_21715) 453739..454065 + 327 WP_011881496.1 anthranilate 1,2-dioxygenase ferredoxin subunit AndAb -
L0Y95_RS21720 (L0Y95_21720) 454055..455275 + 1221 WP_249472952.1 anthranilate 1,2-dioxygenase system ferredoxin--NAD(+) reductase -
L0Y95_RS21725 (L0Y95_21725) 455464..456750 + 1287 WP_014724584.1 DUF445 domain-containing protein -
L0Y95_RS21730 (L0Y95_21730) 456831..457130 - 300 WP_011881499.1 putative addiction module antidote protein Antitoxin
L0Y95_RS21735 (L0Y95_21735) 457134..457472 - 339 WP_249472954.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
L0Y95_RS21740 (L0Y95_21740) 457827..459467 + 1641 WP_249472956.1 acetolactate synthase large subunit -
L0Y95_RS21745 (L0Y95_21745) 459496..460929 + 1434 WP_059453473.1 aldehyde dehydrogenase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(16-109)

Antitoxin

Uncharacterized protein HI1420

(6-93)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12672.44 Da        Isoelectric Point: 9.4958

>T231891 WP_249472954.1 NZ_CP090788:c457472-457134 [Burkholderia vietnamiensis]
MVDISSNVPYSAPTYSIRTTEVFDTWFAGLQDRVARRRIQARIDRLSMGNPGDWKSAGSPVVEMRIDHGPGYRVYYVRRA
TIWVILLCGGDKSTQQADIRTAHAMLGRLDLE

Download         Length: 339 bp

>T231891 NZ_CP126987:2013148-2013250 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10548.87 Da        Isoelectric Point: 6.0633

>AT231891 WP_011881499.1 NZ_CP090788:c457130-456831 [Burkholderia vietnamiensis]
MDKISTRPWDSAAHLETDDDIADYFDACLQEGGDDPAFIAHALGVIARARGMSQVARDAGLSREGLYKALSHDGNPSFGT
ILKVIKALGLQLHGAKARA

Download         Length: 300 bp

>AT231891 NZ_CP126987:c2013257-2013112 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References