Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 791857..792446 Replicon chromosome
Accession NZ_CP090778
Organism Burkholderia multivorans strain 2005Ycf971III

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag L0Y92_RS05685 Protein ID WP_006409935.1
Coordinates 792027..792446 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag L0Y92_RS05680 Protein ID WP_174328801.1
Coordinates 791857..792030 (+) Length 58 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0Y92_RS05655 (L0Y92_05655) 786939..787082 - 144 WP_006409932.1 hypothetical protein -
L0Y92_RS05660 (L0Y92_05660) 787671..787874 + 204 WP_006403067.1 hypothetical protein -
L0Y92_RS05665 (L0Y92_05665) 787888..788571 - 684 WP_006409924.1 Fe2+-dependent dioxygenase -
L0Y92_RS05670 (L0Y92_05670) 788568..789323 - 756 WP_006403069.1 tetratricopeptide repeat protein -
L0Y92_RS05675 (L0Y92_05675) 789327..791573 - 2247 WP_006403070.1 TonB-dependent siderophore receptor -
L0Y92_RS05680 (L0Y92_05680) 791857..792030 + 174 WP_174328801.1 plasmid stability protein Antitoxin
L0Y92_RS05685 (L0Y92_05685) 792027..792446 + 420 WP_006409935.1 type II toxin-antitoxin system VapC family toxin Toxin
L0Y92_RS05690 (L0Y92_05690) 792579..793874 - 1296 WP_035487510.1 aspartate carbamoyltransferase -
L0Y92_RS05695 (L0Y92_05695) 794107..794241 + 135 WP_006409923.1 entericidin A/B family lipoprotein -
L0Y92_RS05700 (L0Y92_05700) 794335..794910 - 576 WP_006409927.1 hypothetical protein -
L0Y92_RS05705 (L0Y92_05705) 795114..796064 - 951 WP_172488721.1 DMT family transporter -
L0Y92_RS05710 (L0Y92_05710) 796577..797371 - 795 WP_006409930.1 AraC family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-122)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15146.38 Da        Isoelectric Point: 5.2157

>T231872 WP_006409935.1 NZ_CP090778:792027-792446 [Burkholderia multivorans]
MILVDTNVIFEPLRREPSAAVIEWLDAQNVETLFLAAISLAEMRFGVAALPEGRRRDWLEQSIEHRVVPVFRGRILPFDD
AAGKAYARIRAHARAVGNAIAPADGYIAATAEANGLIVATRDVAPFEAAGLRVIDPWAS

Download         Length: 420 bp

>T231872 NZ_CP126977:c1813991-1813809 [Gallibacterium anatis]
GTGGATAGTAAAACATTAATAAAAATGCTTGAAAAAGATGGGTGGTACTTGGTGAATGTGGTTGGTAGTCATCATCAATT
TAAACATCCAATAAAGAAAGGGCGGACAACAGTTCCGCATCCCAAAAAGGATTTACAAATAAAAACGGTAAATTCAATAT
TAAAACAAGCGGGCTTGAAATAA

Antitoxin


Download         Length: 58 a.a.        Molecular weight: 6298.07 Da        Isoelectric Point: 4.5184

>AT231872 WP_174328801.1 NZ_CP090778:791857-792030 [Burkholderia multivorans]
MHGRSTEAEVRDILEQAVLSEGRVKLGTLLAEIGREAGGVDLDIQRDKTRTDPMSFE

Download         Length: 174 bp

>AT231872 NZ_CP126977:c1813781-1813374 [Gallibacterium anatis]
ATGTTATATCCGATTGGAATTGAAATGGGTGATGATAAACACGCTTTTGGGGTAATTGTGCCTGATGTGCCAGGTTGTTT
TTCTGCTGGAGATACATTAGAAGAGGCGTATATTAATGCAAAAGAAGCTATCGCTTTTCATATCGAGGGAATGTTAGAAG
ATGGTGAAGAGTTTCCTTTGCCAACCGATATAAAAGCACATATGAATAATAAAGAGTTTGAGGGGTTTACTTTTACTTTT
GTAGATGTTGATTTGTCGCATTTAATGGGTAAAGCGGAAAAAATTAATATTACTCTACCAGCGTTGTTATTACATAAAAT
TGATGCGTTTATTGCAACACATCCAGAGTATAAAAGCCGTAGTGGTTTTTTGGCACAACTTGCAACAGATAAATTACTTT
CAGCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References