Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 971312..971847 Replicon plasmid pRLG201
Accession NC_011368
Organism Rhizobium leguminosarum bv. trifolii WSM2304

Toxin (Protein)


Gene name relE Uniprot ID B6A1P2
Locus tag RLEG2_RS26695 Protein ID WP_003591194.1
Coordinates 971572..971847 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID B6A1P1
Locus tag RLEG2_RS26690 Protein ID WP_003591192.1
Coordinates 971312..971572 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RLEG2_RS26670 967284..968165 - 882 WP_012556165.1 ABC transporter permease -
RLEG2_RS26675 968178..968996 - 819 WP_012556166.1 ABC transporter ATP-binding protein -
RLEG2_RS26680 969092..970105 - 1014 WP_003591189.1 ABC transporter substrate-binding protein -
RLEG2_RS26685 970385..971113 - 729 WP_012556167.1 FadR family transcriptional regulator -
RLEG2_RS26690 971312..971572 + 261 WP_003591192.1 ribbon-helix-helix domain-containing protein Antitoxin
RLEG2_RS26695 971572..971847 + 276 WP_003591194.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
RLEG2_RS26700 971913..972920 - 1008 WP_012556168.1 LacI family transcriptional regulator -
RLEG2_RS26705 973125..974447 + 1323 WP_012556169.1 alpha-L-fucosidase -
RLEG2_RS26710 974497..975717 + 1221 WP_012556170.1 sugar ABC transporter substrate-binding protein -
RLEG2_RS26715 975918..976844 + 927 WP_012556171.1 sugar ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..1266105 1266105


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10849.56 Da        Isoelectric Point: 9.9706

>T23187 WP_003591194.1 NC_011368:971572-971847 [Rhizobium leguminosarum bv. trifolii WSM2304]
MELKWTSKAVSDIDRLYAFLAPVNRQVAARTVQALAAAPLRLLEQPRLGERLEEFDPREVRRILVGRYELRYEIQQSVIY
VLRLWHTREDR

Download         Length: 276 bp

>T23187 NC_011368:971572-971847 [Rhizobium leguminosarum bv. trifolii WSM2304]
ATGGAACTCAAGTGGACGAGCAAGGCGGTCTCGGACATTGATCGCCTTTATGCCTTTCTCGCGCCGGTTAATCGACAGGT
GGCGGCCCGAACCGTGCAGGCATTGGCGGCTGCCCCTCTACGGCTGCTTGAGCAGCCGCGCCTTGGTGAACGGCTGGAGG
AATTCGATCCTCGGGAGGTTCGTCGCATTCTCGTTGGACGGTATGAGCTGCGTTACGAAATCCAGCAGTCAGTCATCTAT
GTATTGCGGCTCTGGCATACGCGAGAAGACCGGTAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9653.00 Da        Isoelectric Point: 6.4650

>AT23187 WP_003591192.1 NC_011368:971312-971572 [Rhizobium leguminosarum bv. trifolii WSM2304]
MKTKVLTAHVPLPLAQKVDQLAARLERSRGWIVKQALTAWIDQEEERRRLTLEALADVDKGNVVDHQSVQAWADSLDSDA
PVSLPR

Download         Length: 261 bp

>AT23187 NC_011368:971312-971572 [Rhizobium leguminosarum bv. trifolii WSM2304]
ATGAAAACCAAAGTGCTGACCGCGCATGTCCCTCTGCCCCTTGCACAGAAGGTCGATCAACTCGCGGCGAGACTTGAGCG
TTCGCGCGGCTGGATCGTCAAGCAGGCGCTGACGGCGTGGATCGATCAAGAAGAGGAGCGTCGCCGTTTGACGCTAGAGG
CGCTGGCTGACGTGGACAAAGGTAATGTCGTCGATCACCAGTCCGTTCAGGCTTGGGCCGATAGCCTCGACAGCGATGCG
CCGGTTTCGCTGCCTCGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7Z0IXN7

Antitoxin

Source ID Structure
AlphaFold DB A0A7Z0IX85

References