Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/upstrm_HI1419-dnstrm_HI1420 |
Location | 2245493..2246134 | Replicon | chromosome |
Accession | NZ_CP090761 | ||
Organism | Burkholderia cenocepacia strain 2009Ycf95III |
Toxin (Protein)
Gene name | relE | Uniprot ID | - |
Locus tag | L0Z39_RS30790 | Protein ID | WP_276209001.1 |
Coordinates | 2245493..2245831 (+) | Length | 113 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | - |
Locus tag | L0Z39_RS30795 | Protein ID | WP_062885379.1 |
Coordinates | 2245835..2246134 (+) | Length | 100 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
L0Z39_RS30780 (L0Z39_30780) | 2242023..2243456 | - | 1434 | WP_006490987.1 | aldehyde dehydrogenase family protein | - |
L0Z39_RS30785 (L0Z39_30785) | 2243485..2245125 | - | 1641 | WP_006490980.1 | acetolactate synthase large subunit | - |
L0Z39_RS30790 (L0Z39_30790) | 2245493..2245831 | + | 339 | WP_276209001.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
L0Z39_RS30795 (L0Z39_30795) | 2245835..2246134 | + | 300 | WP_062885379.1 | putative addiction module antidote protein | Antitoxin |
L0Z39_RS30800 (L0Z39_30800) | 2246183..2247469 | - | 1287 | WP_006490986.1 | DUF445 domain-containing protein | - |
L0Z39_RS30805 (L0Z39_30805) | 2247579..2248799 | - | 1221 | WP_205670709.1 | anthranilate 1,2-dioxygenase system ferredoxin--NAD(+) reductase | - |
L0Z39_RS30810 (L0Z39_30810) | 2248789..2249115 | - | 327 | WP_006496019.1 | anthranilate 1,2-dioxygenase ferredoxin subunit AndAb | - |
L0Z39_RS30815 (L0Z39_30815) | 2249151..2249627 | - | 477 | WP_006490977.1 | anthranilate 1,2-dioxygenase small subunit AndAd | - |
L0Z39_RS30820 (L0Z39_30820) | 2249643..2250914 | - | 1272 | WP_205670708.1 | anthranilate 1,2-dioxygenase large subunit AndAc | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 113 a.a. Molecular weight: 12604.50 Da Isoelectric Point: 7.8496
>T231830 WP_276209001.1 NZ_CP090761:2245493-2245831 [Burkholderia cenocepacia]
MVYTLQCMPYSPPAFGIRTTDVFDAWFAGLPDRLAKRRIQARIDRLSMGNPGDWKSAGSPVVEMRIDHGPGYRVYDVRRG
TIWVILLCGGDQSTQQADIRAAHAMLAYLDME
MVYTLQCMPYSPPAFGIRTTDVFDAWFAGLPDRLAKRRIQARIDRLSMGNPGDWKSAGSPVVEMRIDHGPGYRVYDVRRG
TIWVILLCGGDQSTQQADIRAAHAMLAYLDME
Download Length: 339 bp
>T231830 NZ_CP126955:c4299221-4298694 [Escherichia coli O78:H4]
ATGGATGATCTGACGATAGAGATTCTGACCGATGATGCAGATTATGATCTACAGCGATTCGACTGCGGCGAGGAAGCGTT
AAATCTCTTTCTGACGACACATCTCGTTCGTCAACATCGCAACAAAATTCTGCGAGCGTATATCCTTTGTCGCAACACTC
CAGAACGTCAGGTGCTGGGATATTACACATTATGCGGCAGTTGTTTTGAACGAGCCGCATTGCCCTCGAAATCGAAACAG
AAAAAAATTCCCTACAAAAATATTCCCAGCGTTACTCTTGGGCGTCTGGCAATTGATCGTTCATTACAGGGGCAGGGATG
GGGAGCAACACTGGTTGCTCATGCCATGAAAGTCGTCTGGTCAGCCTCTTTAGCGGTAGGTATTCACGGTCTTTTTGTCG
AGGCGCTGAATAAAAAAGCCCATACGTTTTATCAATCGCTGGGCTTTATCCCGTTGGTCGGAGAAAACGAAAATGCGTTA
TTTTTCCCAACCAAATCCATCGAACTGCTTTTCACACAGAGCGATTAA
ATGGATGATCTGACGATAGAGATTCTGACCGATGATGCAGATTATGATCTACAGCGATTCGACTGCGGCGAGGAAGCGTT
AAATCTCTTTCTGACGACACATCTCGTTCGTCAACATCGCAACAAAATTCTGCGAGCGTATATCCTTTGTCGCAACACTC
CAGAACGTCAGGTGCTGGGATATTACACATTATGCGGCAGTTGTTTTGAACGAGCCGCATTGCCCTCGAAATCGAAACAG
AAAAAAATTCCCTACAAAAATATTCCCAGCGTTACTCTTGGGCGTCTGGCAATTGATCGTTCATTACAGGGGCAGGGATG
GGGAGCAACACTGGTTGCTCATGCCATGAAAGTCGTCTGGTCAGCCTCTTTAGCGGTAGGTATTCACGGTCTTTTTGTCG
AGGCGCTGAATAAAAAAGCCCATACGTTTTATCAATCGCTGGGCTTTATCCCGTTGGTCGGAGAAAACGAAAATGCGTTA
TTTTTCCCAACCAAATCCATCGAACTGCTTTTCACACAGAGCGATTAA
Antitoxin
Download Length: 100 a.a. Molecular weight: 10622.07 Da Isoelectric Point: 6.4771
>AT231830 WP_062885379.1 NZ_CP090761:2245835-2246134 [Burkholderia cenocepacia]
MDKIKTRPWDSAEHLKTEDDMADYFDACLQEAGDDPAFIAHALGVIARARGMSQVARDAGLSREGLYKALSHDGNPSFGT
ILKVIKALGLQLHAAKAAA
MDKIKTRPWDSAEHLKTEDDMADYFDACLQEAGDDPAFIAHALGVIARARGMSQVARDAGLSREGLYKALSHDGNPSFGT
ILKVIKALGLQLHAAKAAA
Download Length: 300 bp
>AT231830 NZ_CP126955:c4299494-4299228 [Escherichia coli O78:H4]
ATGTCTGCTGTTAAAAAGCAGCGTATCGATCTGCGTTTAACTGACGATGACAAAAGTATGATTGAGGAAGCGGCAGCGAT
ATCTAATCAGTCCGTCAGCCAATTTATGTTGAACAGCGCTTCGCAGCGGGCTGCGGAAGTGATTGAACAGCATCGGCGGG
TGATCCTCAATGAGGAATCCTGGACGCGGGTGATGGATGCGCTGAGTAATCCACCGTCACCTGGTGAAAAGCTAAAACGT
GCGGCAAAACGTCTTCAGGGAATGTAA
ATGTCTGCTGTTAAAAAGCAGCGTATCGATCTGCGTTTAACTGACGATGACAAAAGTATGATTGAGGAAGCGGCAGCGAT
ATCTAATCAGTCCGTCAGCCAATTTATGTTGAACAGCGCTTCGCAGCGGGCTGCGGAAGTGATTGAACAGCATCGGCGGG
TGATCCTCAATGAGGAATCCTGGACGCGGGTGATGGATGCGCTGAGTAATCCACCGTCACCTGGTGAAAAGCTAAAACGT
GCGGCAAAACGTCTTCAGGGAATGTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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