Detailed information of TA system TA023182

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-StbC
• Location: 3313611..3314284
• Replicon: chromosome
• Accession: NC_011365
• Organism: Gluconacetobacter diazotrophicus PAl 5

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: A9H385
• Locus tag: GDIA_RS15180
• Protein ID: WP_012227838.1
• Coordinates: 3313611..3314033 (-)
• Length: 141 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: A9H383
• Locus tag: GDIA_RS15185
• Protein ID: WP_012227836.1
• Coordinates: 3314030..3314284 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (2-122)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 141 a.a.
• Molecular weight: 15216.50 Da
• Isoelectric Point: 4.8485

>T23182 WP_012227838.1 NC_011365:c3314033-3313611 [Gluconacetobacter diazotrophicus PA1 5]
MILLDTNVVSEPWKPVPEPRVLEWIDAQAIETLWLSAVTVAELRFGIAAMPAGRRRSILHQSLEQDVLPLFDGRVLPFDL
AASQAYADLMMRARSDGRAIGQADGYIAAIAASRGYAVASRDVSPFEAAGVKILNPWQGA

Nucleotide

• Length: 423 bp

>T23182 NC_011365:c3314033-3313611 [Gluconacetobacter diazotrophicus PA1 5]
ATGATCCTTCTTGATACCAATGTGGTCTCGGAGCCATGGAAGCCTGTTCCTGAACCGCGTGTCCTGGAATGGATCGACGC
CCAGGCGATCGAGACGCTGTGGCTGTCGGCCGTCACGGTGGCGGAATTGCGATTCGGAATTGCCGCCATGCCGGCAGGCC
GGCGGCGTTCGATCCTGCATCAGAGTCTGGAACAGGACGTTCTGCCCCTGTTCGACGGGCGTGTCCTGCCCTTCGATCTG
GCGGCGTCCCAGGCTTATGCAGATCTGATGATGCGGGCCAGGTCCGATGGACGGGCGATCGGCCAGGCGGACGGCTATAT
TGCCGCAATTGCCGCATCCCGCGGTTACGCGGTGGCCAGTCGGGATGTGTCGCCGTTCGAGGCGGCCGGTGTGAAGATCC
TGAATCCGTGGCAGGGCGCCTGA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9236.54 Da
• Isoelectric Point: 6.7262

>AT23182 WP_012227836.1 NC_011365:c3314284-3314030 [Gluconacetobacter diazotrophicus PA1 5]
MSSVVIRNLPEETHRALKARAALHGHSTEAEIRAILEAVVRPPKRVRLGSLLASIGREADVTEQDVAALQQVRDQTPAEP
MTFE

Nucleotide

• Length: 255 bp

>AT23182 NC_011365:c3314284-3314030 [Gluconacetobacter diazotrophicus PA1 5]
ATGTCCTCTGTCGTCATCCGCAATCTTCCCGAAGAGACGCATCGGGCGCTGAAAGCGCGGGCCGCCCTGCATGGACACAG
CACGGAAGCGGAAATCCGCGCCATTCTGGAAGCCGTCGTCCGGCCGCCGAAGCGCGTCAGGCTGGGGTCGCTTCTGGCGT
CCATAGGTCGTGAAGCCGACGTGACCGAGCAGGATGTCGCGGCCTTGCAGCAGGTTCGGGATCAGACCCCAGCCGAGCCG
ATGACATTCGAATGA

Structures

Toxin

• AlphaFold DB: A9H385

Antitoxin

• AlphaFold DB: A9H383