Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 801798..802387 Replicon chromosome
Accession NZ_CP090686
Organism Burkholderia multivorans strain 2019Y60005016V

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag L0Y84_RS05740 Protein ID WP_006409935.1
Coordinates 801968..802387 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag L0Y84_RS05735 Protein ID WP_174328801.1
Coordinates 801798..801971 (+) Length 58 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0Y84_RS05710 (L0Y84_05710) 796880..797023 - 144 WP_006409932.1 hypothetical protein -
L0Y84_RS05715 (L0Y84_05715) 797612..797815 + 204 WP_006403067.1 hypothetical protein -
L0Y84_RS05720 (L0Y84_05720) 797829..798512 - 684 WP_006409924.1 Fe2+-dependent dioxygenase -
L0Y84_RS05725 (L0Y84_05725) 798509..799264 - 756 WP_006403069.1 tetratricopeptide repeat protein -
L0Y84_RS05730 (L0Y84_05730) 799268..801514 - 2247 WP_006403070.1 TonB-dependent siderophore receptor -
L0Y84_RS05735 (L0Y84_05735) 801798..801971 + 174 WP_174328801.1 plasmid stability protein Antitoxin
L0Y84_RS05740 (L0Y84_05740) 801968..802387 + 420 WP_006409935.1 type II toxin-antitoxin system VapC family toxin Toxin
L0Y84_RS05745 (L0Y84_05745) 802520..803815 - 1296 WP_035487510.1 aspartate carbamoyltransferase -
L0Y84_RS05750 (L0Y84_05750) 804048..804182 + 135 WP_006409923.1 entericidin A/B family lipoprotein -
L0Y84_RS05755 (L0Y84_05755) 804276..804851 - 576 WP_006409927.1 hypothetical protein -
L0Y84_RS05760 (L0Y84_05760) 805055..806005 - 951 WP_172488721.1 DMT family transporter -
L0Y84_RS05765 (L0Y84_05765) 806518..807312 - 795 WP_006409930.1 AraC family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-122)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15146.38 Da        Isoelectric Point: 5.2157

>T231620 WP_006409935.1 NZ_CP090686:801968-802387 [Burkholderia multivorans]
MILVDTNVIFEPLRREPSAAVIEWLDAQNVETLFLAAISLAEMRFGVAALPEGRRRDWLEQSIEHRVVPVFRGRILPFDD
AAGKAYARIRAHARAVGNAIAPADGYIAATAEANGLIVATRDVAPFEAAGLRVIDPWAS

Download         Length: 420 bp

>T231620 NZ_CP126937:215595-215702 [Escherichia coli O2:K1:H4]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCACGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 58 a.a.        Molecular weight: 6298.07 Da        Isoelectric Point: 4.5184

>AT231620 WP_174328801.1 NZ_CP090686:801798-801971 [Burkholderia multivorans]
MHGRSTEAEVRDILEQAVLSEGRVKLGTLLAEIGREAGGVDLDIQRDKTRTDPMSFE

Download         Length: 174 bp

>AT231620 NZ_CP126937:c215546-215481 [Escherichia coli O2:K1:H4]
GTCTAGATGCAAGAATGGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References