Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 2106041..2106636 Replicon chromosome
Accession NZ_CP090681
Organism Burkholderia multivorans strain 2019Y71417852IX

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag L0Z03_RS09255 Protein ID WP_105834886.1
Coordinates 2106286..2106636 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag L0Z03_RS09250 Protein ID WP_105834901.1
Coordinates 2106041..2106292 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0Z03_RS09235 (L0Z03_09235) 2101477..2102448 - 972 WP_006397255.1 LysR family transcriptional regulator -
L0Z03_RS09240 (L0Z03_09240) 2102590..2103894 + 1305 WP_039222447.1 MFS transporter -
L0Z03_RS09245 (L0Z03_09245) 2103995..2105488 + 1494 WP_105834887.1 M81 family metallopeptidase -
L0Z03_RS09250 (L0Z03_09250) 2106041..2106292 + 252 WP_105834901.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
L0Z03_RS09255 (L0Z03_09255) 2106286..2106636 + 351 WP_105834886.1 type II toxin-antitoxin system ChpB family toxin Toxin
L0Z03_RS09260 (L0Z03_09260) 2106815..2108350 - 1536 WP_249458847.1 multidrug efflux transporter outer membrane subunit OpcM -
L0Z03_RS09265 (L0Z03_09265) 2108361..2111546 - 3186 WP_249458849.1 multidrug efflux RND transporter permease subunit CeoB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-114)

Antitoxin

SpoVT-AbrB domain

(6-49)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12356.39 Da        Isoelectric Point: 10.4367

>T231616 WP_105834886.1 NZ_CP090681:2106286-2106636 [Burkholderia multivorans]
MVKRVKFERGDIVRVSLNPTLGREQQGDFRPALVLSPAAFNALGVALVAPITQGGEFARFAGFAVPLSGAGTATQGVALV
NMVRMLDLEARGARKVERAPVEVVEDALARLQTIIE

Download         Length: 351 bp

>T231616 NZ_CP126935:66841-67119 [Escherichia coli O78:H4]
ATGGAGATATTCTGGACCATGCTGGCCAGCCAGGACAGGAAGCGCATTCGTGAGTACATTGCGGAGCAGAACCTGATGGC
CGCCATTGAACTGGACGAGCGGATTGGTTATTCAGCCAGCAGCCTGGCCGGGCAGCCGTATAAAGGCCGCAATGGTCGTG
TGGAAGGTACCCGGGAACTGGTTATTCACCCGCATTTTGTTCTGGTTTATGAGGTCGACAGCCAGTGGGGAAAAGTGTAT
ATCCTGCGCGTGTTGCATACTGCACAGAAGTGGCCATAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 8993.33 Da        Isoelectric Point: 6.2420

>AT231616 WP_105834901.1 NZ_CP090681:2106041-2106292 [Burkholderia multivorans]
MELKIQKWGNSAAVRLPSVLLEQINATVGSSLSADVRPDGVLLTPARRKYSLDDLVAQCDTKAPFPADMGAWGEVKPVGR
EAW

Download         Length: 252 bp

>AT231616 NZ_CP126935:66572-66841 [Escherichia coli O78:H4]
ATGGCACAGGTTAATATGAGTTTAAGAATCGACGCTGAACTGAAGGATGCTTTTATGGCCGCTGCAAAAAGCATGGACCG
TAATGGCTCTCAGTTAATCCGGGATTTTATGCGCCAGACCGTTGAACAACAGCATAATACCTGGTTCCGTGACCAGGTTG
CGGCAGGACGTCAGCAACTCGAGCACGGCGATGTGCTTCCCCATGACATGGTCGAATCCTCCGCTACTGCATGGCGGGAT
GAAATGAGCAGGAAGGTTGCCGGTAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References