Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapC-vagC/VapC-VagC |
Location | 298595..299232 | Replicon | chromosome |
Accession | NZ_CP090676 | ||
Organism | Burkholderia cenocepacia strain 2019Y71443953II |
Toxin (Protein)
Gene name | vapC | Uniprot ID | - |
Locus tag | L0Y99_RS05940 | Protein ID | WP_205671571.1 |
Coordinates | 298595..298996 (-) | Length | 134 a.a. |
Antitoxin (Protein)
Gene name | vagC | Uniprot ID | A0A364GPY9 |
Locus tag | L0Y99_RS05945 | Protein ID | WP_034201144.1 |
Coordinates | 298996..299232 (-) | Length | 79 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
L0Y99_RS05930 (L0Y99_05930) | 295979..297109 | + | 1131 | WP_085964363.1 | alginate lyase family protein | - |
L0Y99_RS05935 (L0Y99_05935) | 297140..298528 | + | 1389 | WP_077190293.1 | L-serine ammonia-lyase | - |
L0Y99_RS05940 (L0Y99_05940) | 298595..298996 | - | 402 | WP_205671571.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
L0Y99_RS05945 (L0Y99_05945) | 298996..299232 | - | 237 | WP_034201144.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin |
L0Y99_RS05950 (L0Y99_05950) | 299350..299579 | - | 230 | Protein_288 | type II toxin-antitoxin system RelE/ParE family toxin | - |
L0Y99_RS05955 (L0Y99_05955) | 299948..301651 | + | 1704 | WP_205671570.1 | thiamine pyrophosphate-binding protein | - |
L0Y99_RS05960 (L0Y99_05960) | 301648..302745 | + | 1098 | WP_200063711.1 | ADP-heptose--LPS heptosyltransferase | - |
L0Y99_RS05965 (L0Y99_05965) | 302840..303856 | - | 1017 | WP_006493582.1 | helix-turn-helix domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 134 a.a. Molecular weight: 15039.29 Da Isoelectric Point: 6.2245
>T231593 WP_205671571.1 NZ_CP090676:c298996-298595 [Burkholderia cenocepacia]
MPRFMLDTNMCIYLMKNQPEQVARRFARCYTGDVVMSAITYAELECGLTACVNPARERRHLAALIEDIPVAPFDAAAAQA
YGPVREATRERKKDHLDKLIAAHAVSLDVVLVTNNERDFVSYPGLRLENWLND
MPRFMLDTNMCIYLMKNQPEQVARRFARCYTGDVVMSAITYAELECGLTACVNPARERRHLAALIEDIPVAPFDAAAAQA
YGPVREATRERKKDHLDKLIAAHAVSLDVVLVTNNERDFVSYPGLRLENWLND
Download Length: 402 bp
>T231593 NZ_CP126932:c147988-147572 [Escherichia coli O78:H51]
GTGAACAAGATCTATATGCTCGACACGAACATCTGCTCGTTCATCATGCGCGAGCAACCTGAAGCATTGCTTAAGCACCT
GGAGCAGTCGGTGCTGCGCGGTCACCGTATCGTGGTCTCGGCCATCACCTACTCCGAGATGCGCTTCGGTGCCACCGGTC
CGAAGGCCTCGCCACGCCACGTGCAACTGGTTGACGCGTTCTGTGAGAGGCTCGATGCCGTCCTGCCGTGGGACCGCGCC
GCGGTGGATGCGACCACGGAGATTAAGGTGGCACTGCGTCTCGCCGGCACGCCGATCGGTCCGAACGACACGGCGATAGC
CGGACACGCCATCGCTGCCTGTGCCATTCTGGTGACGAATAATGTGAGAGAGTTTGAGCGGGTACCGGGTCTTGTGCTGG
AAGACTGGGTAAGATAA
GTGAACAAGATCTATATGCTCGACACGAACATCTGCTCGTTCATCATGCGCGAGCAACCTGAAGCATTGCTTAAGCACCT
GGAGCAGTCGGTGCTGCGCGGTCACCGTATCGTGGTCTCGGCCATCACCTACTCCGAGATGCGCTTCGGTGCCACCGGTC
CGAAGGCCTCGCCACGCCACGTGCAACTGGTTGACGCGTTCTGTGAGAGGCTCGATGCCGTCCTGCCGTGGGACCGCGCC
GCGGTGGATGCGACCACGGAGATTAAGGTGGCACTGCGTCTCGCCGGCACGCCGATCGGTCCGAACGACACGGCGATAGC
CGGACACGCCATCGCTGCCTGTGCCATTCTGGTGACGAATAATGTGAGAGAGTTTGAGCGGGTACCGGGTCTTGTGCTGG
AAGACTGGGTAAGATAA
Antitoxin
Download Length: 79 a.a. Molecular weight: 8982.15 Da Isoelectric Point: 6.4701
>AT231593 WP_034201144.1 NZ_CP090676:c299232-298996 [Burkholderia cenocepacia]
MHTTRVFRNGNSQAVRIPADLAYERSDIELEIERVGDEIRIRPMRRPLTQVLAKFAKFGPDFMADGRGDHEQAEREGL
MHTTRVFRNGNSQAVRIPADLAYERSDIELEIERVGDEIRIRPMRRPLTQVLAKFAKFGPDFMADGRGDHEQAEREGL
Download Length: 237 bp
>AT231593 NZ_CP126932:c148215-147985 [Escherichia coli O78:H51]
ATGAGAACCGTATCCATTTTTAAAAATGGCAACAACCGTGCTATCCGCCTTCCACGCGATCTGGATTTTGAGGGGGTGAG
CGAGCTGGAGATCGTCCGGGAAGGGGACAGCATCATTCTGCGCCCCGTCCGACCGACCTGGGGCTCATTCCTGGAGCTAG
AAAAGGCCGATCCGGACTTTATGACGGAGCGCGAGGACGTTGTCAGCGACGAAGGACGAGTTAACCTGTGA
ATGAGAACCGTATCCATTTTTAAAAATGGCAACAACCGTGCTATCCGCCTTCCACGCGATCTGGATTTTGAGGGGGTGAG
CGAGCTGGAGATCGTCCGGGAAGGGGACAGCATCATTCTGCGCCCCGTCCGACCGACCTGGGGCTCATTCCTGGAGCTAG
AAAAGGCCGATCCGGACTTTATGACGGAGCGCGAGGACGTTGTCAGCGACGAAGGACGAGTTAACCTGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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