Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/VapC-StbC |
| Location | 241035..241674 | Replicon | chromosome |
| Accession | NZ_CP090641 | ||
| Organism | Burkholderia contaminans strain LMG 23361 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | LXE91_RS18890 | Protein ID | WP_223274309.1 |
| Coordinates | 241035..241451 (-) | Length | 139 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | A0A1X1PQC0 |
| Locus tag | LXE91_RS18895 | Protein ID | WP_039351245.1 |
| Coordinates | 241438..241674 (-) | Length | 79 a.a. |
Genomic Context
Location: 236202..237290 (1089 bp)
Type: Others
Protein ID: WP_039350864.1
Type: Others
Protein ID: WP_039350864.1
Location: 237287..238219 (933 bp)
Type: Others
Protein ID: WP_039350867.1
Type: Others
Protein ID: WP_039350867.1
Location: 238228..239025 (798 bp)
Type: Others
Protein ID: WP_039350869.1
Type: Others
Protein ID: WP_039350869.1
Location: 239036..239929 (894 bp)
Type: Others
Protein ID: WP_039350872.1
Type: Others
Protein ID: WP_039350872.1
Location: 239939..240835 (897 bp)
Type: Others
Protein ID: WP_039350875.1
Type: Others
Protein ID: WP_039350875.1
Location: 241035..241451 (417 bp)
Type: Toxin
Protein ID: WP_223274309.1
Type: Toxin
Protein ID: WP_223274309.1
Location: 241438..241674 (237 bp)
Type: Antitoxin
Protein ID: WP_039351245.1
Type: Antitoxin
Protein ID: WP_039351245.1
Location: 242048..242707 (660 bp)
Type: Others
Protein ID: WP_046196544.1
Type: Others
Protein ID: WP_046196544.1
Location: 243500..244273 (774 bp)
Type: Others
Protein ID: WP_039351252.1
Type: Others
Protein ID: WP_039351252.1
Location: 244312..245892 (1581 bp)
Type: Others
Protein ID: WP_039350882.1
Type: Others
Protein ID: WP_039350882.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LXE91_RS18865 (LXE91_18795) | 236202..237290 | - | 1089 | WP_039350864.1 | nitronate monooxygenase | - |
| LXE91_RS18870 (LXE91_18800) | 237287..238219 | - | 933 | WP_039350867.1 | enoyl-CoA hydratase | - |
| LXE91_RS18875 (LXE91_18805) | 238228..239025 | - | 798 | WP_039350869.1 | ketoacid CoA transferase | - |
| LXE91_RS18880 (LXE91_18810) | 239036..239929 | - | 894 | WP_039350872.1 | CoA-transferase | - |
| LXE91_RS18885 (LXE91_18815) | 239939..240835 | - | 897 | WP_039350875.1 | VOC family protein | - |
| LXE91_RS18890 (LXE91_18820) | 241035..241451 | - | 417 | WP_223274309.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
| LXE91_RS18895 (LXE91_18825) | 241438..241674 | - | 237 | WP_039351245.1 | DNA-binding protein | Antitoxin |
| LXE91_RS18900 (LXE91_18830) | 242048..242707 | - | 660 | WP_046196544.1 | hypothetical protein | - |
| LXE91_RS18905 (LXE91_18835) | 243500..244273 | - | 774 | WP_039351252.1 | SDR family oxidoreductase | - |
| LXE91_RS18910 (LXE91_18840) | 244312..245892 | - | 1581 | WP_039350882.1 | FadD3 family acyl-CoA ligase | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 139 a.a. Molecular weight: 15370.68 Da Isoelectric Point: 7.4021
>T231553 WP_223274309.1 NZ_CP090641:c241451-241035 [Burkholderia contaminans]
VYLIDTNIISEIRKGKRTNRGVRAFFRQAAADASPLYLSVVTVAELRRGVDLIRHRGDHPQASALEAWMATILSGYAPNI
LPVDIEISQMWGHLRVPDPTHELDKLIAATALINDLTVVTRNVEDFARTGVKLLNPFD
VYLIDTNIISEIRKGKRTNRGVRAFFRQAAADASPLYLSVVTVAELRRGVDLIRHRGDHPQASALEAWMATILSGYAPNI
LPVDIEISQMWGHLRVPDPTHELDKLIAATALINDLTVVTRNVEDFARTGVKLLNPFD
Download Length: 417 bp
>T231553 NZ_CP126928:c3530184-3529882 [Escherichia coli O2:K1:H4]
ATGGCTCAAAAGAAAAATATAAGGAGTTTTCGTGATGCCTGGTTGGCTGATTTTTTTGTCCATTCAACGCCACATCGAAA
GATCCCTGCTGAAATCCATACCACGTTATCACGAAAGTTGGACATCATTAATGCTGCCACTTCTCATTGGGATTTACGCT
CCCCTCCGGGGAACCGATACGAAGAGTTATCCGGGAAATTACAGGAATACTCCTCCATTAGAGTGAATAAACAGTACCGA
CTGATTTTTAAATGGGTTAATGGCAAGGCCGAAGAATTGTTTTTAGACCCACACAACTACTAA
ATGGCTCAAAAGAAAAATATAAGGAGTTTTCGTGATGCCTGGTTGGCTGATTTTTTTGTCCATTCAACGCCACATCGAAA
GATCCCTGCTGAAATCCATACCACGTTATCACGAAAGTTGGACATCATTAATGCTGCCACTTCTCATTGGGATTTACGCT
CCCCTCCGGGGAACCGATACGAAGAGTTATCCGGGAAATTACAGGAATACTCCTCCATTAGAGTGAATAAACAGTACCGA
CTGATTTTTAAATGGGTTAATGGCAAGGCCGAAGAATTGTTTTTAGACCCACACAACTACTAA
Antitoxin
Download Length: 79 a.a. Molecular weight: 8598.61 Da Isoelectric Point: 5.0477
>AT231553 WP_039351245.1 NZ_CP090641:c241674-241438 [Burkholderia contaminans]
MANLLVRNVDDSIVQSLREQAAANGRSAEAEHRAILADALGRPKRKTFAQVLMSMPDVGDDADFQRVQDSGEARRVFD
MANLLVRNVDDSIVQSLREQAAANGRSAEAEHRAILADALGRPKRKTFAQVLMSMPDVGDDADFQRVQDSGEARRVFD
Download Length: 237 bp
>AT231553 NZ_CP126928:c3529846-3529505 [Escherichia coli O2:K1:H4]
ATGAAACAGGCAACAAGAAAACCGACGACACCCGGAGATATTCTTCTCTATGAATATCTGGAACCGCTCGATTTGAAAAT
CAATGAGTTAGCAGAGTTGCTGCATGTTCATCGTAATAGCGTCAGTGCACTGATCAATAACAATCGTAAACTCACCACTG
AGATGGCATTCCGTCTGGCGAAAGTTTTTGATACCACAGTCGATTTTTGGCTAAACCTCCAGGCGGCAGTTGATCTTTGG
GAAGTTGAAAACAACATGCGTACCCAGGAAGAATTGGGACGGATTGAAACAGTGGCTGAATATTTGGCACGCCGTGAAGA
GCGTGCAAAAAAGGTCGCGTAG
ATGAAACAGGCAACAAGAAAACCGACGACACCCGGAGATATTCTTCTCTATGAATATCTGGAACCGCTCGATTTGAAAAT
CAATGAGTTAGCAGAGTTGCTGCATGTTCATCGTAATAGCGTCAGTGCACTGATCAATAACAATCGTAAACTCACCACTG
AGATGGCATTCCGTCTGGCGAAAGTTTTTGATACCACAGTCGATTTTTGGCTAAACCTCCAGGCGGCAGTTGATCTTTGG
GAAGTTGAAAACAACATGCGTACCCAGGAAGAATTGGGACGGATTGAAACAGTGGCTGAATATTTGGCACGCCGTGAAGA
GCGTGCAAAAAAGGTCGCGTAG
Structures
Toxin
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Source | ID | Structure |
|---|---|---|
| No matching records found | ||
Antitoxin
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Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A1X1PQC0 |