Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 1095214..1095809 Replicon chromosome
Accession NZ_CP090637
Organism Burkholderia contaminans strain FFI45

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag LXE92_RS36790 Protein ID WP_278133997.1
Coordinates 1095214..1095564 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag LXE92_RS36795 Protein ID WP_071336241.1
Coordinates 1095558..1095809 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LXE92_RS36780 (LXE92_36740) 1092067..1093526 + 1460 Protein_991 efflux RND transporter periplasmic adaptor subunit -
LXE92_RS36785 (LXE92_36745) 1093558..1095090 + 1533 WP_278133995.1 efflux transporter outer membrane subunit -
LXE92_RS36790 (LXE92_36750) 1095214..1095564 - 351 WP_278133997.1 type II toxin-antitoxin system ChpB family toxin Toxin
LXE92_RS36795 (LXE92_36755) 1095558..1095809 - 252 WP_071336241.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
LXE92_RS36800 (LXE92_36760) 1095977..1096132 - 156 WP_278135468.1 hypothetical protein -
LXE92_RS36805 (LXE92_36765) 1096176..1096460 + 285 Protein_996 RND transporter -
LXE92_RS36810 (LXE92_36770) 1096786..1098606 + 1821 WP_278134000.1 asparagine synthase (glutamine-hydrolyzing) -
LXE92_RS36815 (LXE92_36775) 1098841..1100301 - 1461 WP_278134002.1 heavy metal sensor histidine kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-114)

Antitoxin

SpoVT-AbrB domain

(6-49)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12384.25 Da        Isoelectric Point: 8.7082

>T231546 WP_278133997.1 NZ_CP090637:c1095564-1095214 [Burkholderia contaminans]
MVRRVKFERGDIVRVSLNPTVGKEQQGDFRPALVLSPAAFNALGVALVAPITQGGEFARYAGFAVPLSGSGTETQGVALV
NMVRTLDLQAHGARKVERAPSEVIEDALARLQTILE

Download         Length: 351 bp

>T231546 NZ_CP126928:1929273-1929524 [Escherichia coli O2:K1:H4]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGCTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 8890.15 Da        Isoelectric Point: 5.0188

>AT231546 WP_071336241.1 NZ_CP090637:c1095809-1095558 [Burkholderia contaminans]
MELKIQKWGNSAAVRLPAVLLEQIGASVGSSLNADVRPDGVLLSPARRKYSLDELIAQCDPKAPEPADLAAWGESKPVGH
EAW

Download         Length: 252 bp

>AT231546 NZ_CP126928:1929521-1929775 [Escherichia coli O2:K1:H4]
GTGAAACTAATCTGGTCTGAGGAGTCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACACCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References