Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 917150..917669 Replicon chromosome
Accession NZ_CP090636
Organism Burkholderia contaminans strain FFI45

Toxin (Protein)


Gene name relE Uniprot ID A0A1E3FLI5
Locus tag LXE92_RS21735 Protein ID WP_039349649.1
Coordinates 917388..917669 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A4V2WFY1
Locus tag LXE92_RS21730 Protein ID WP_039349647.1
Coordinates 917150..917398 (+) Length 83 a.a.

Genomic Context

LXE92_RS21720LXE92_RS21725LXE92_RS21730LXE92_RS21735LXE92_RS21745LXE92_RS21755LXE92_RS21740LXE92_RS21750
Location: 914582..915772 (1191 bp)
Type: Others
Protein ID: WP_046548712.1
Location: 915956..917008 (1053 bp)
Type: Others
Protein ID: WP_278132880.1
Location: 917150..917398 (249 bp)
Type: Antitoxin
Protein ID: WP_039349647.1
Location: 917388..917669 (282 bp)
Type: Toxin
Protein ID: WP_039349649.1
Location: 918500..920119 (1620 bp)
Type: Others
Protein ID: WP_278132882.1
Location: 921316..922014 (699 bp)
Type: Others
Protein ID: WP_278132887.1
Location: 917787..918230 (444 bp)
Type: Others
Protein ID: WP_011353771.1
Location: 920092..921201 (1110 bp)
Type: Others
Protein ID: WP_278132884.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
LXE92_RS21720 (LXE92_21660)914582..915772+1191WP_046548712.12-methylaconitate cis-trans isomerase PrpF-
LXE92_RS21725 (LXE92_21665)915956..917008+1053WP_278132880.1CaiB/BaiF CoA-transferase family protein-
LXE92_RS21730 (LXE92_21670)917150..917398+249WP_039349647.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
LXE92_RS21735 (LXE92_21675)917388..917669+282WP_039349649.1type II toxin-antitoxin system RelE/ParE family toxinToxin
LXE92_RS21740 (LXE92_21680)917787..918230-444WP_011353771.1PaaI family thioesterase-
LXE92_RS21745 (LXE92_21685)918500..920119+1620WP_278132882.1methyl-accepting chemotaxis protein-
LXE92_RS21750 (LXE92_21690)920092..921201-1110WP_278132884.1AGE family epimerase/isomerase-
LXE92_RS21755 (LXE92_21695)921316..922014+699WP_278132887.1MgtC/SapB family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-81)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(12-78)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10986.88 Da        Isoelectric Point: 10.7091

>T231538 WP_039349649.1 NZ_CP090636:917388-917669 [Burkholderia contaminans]
MTFELAFLEPALKEWKKLDRTVRDQFKSRLAERLENPRIPSAKLQGHPDRYKIKLRSVGYRLVYEVRDSEVLVLVVAVGR
RERDAVYLAAMKR

Download         Length: 282 bp

>T231538 NZ_CP126927:c141830-141681 [Escherichia coli O2:K1:H5]
ATGACGAAATATGCCCTTATCGGGTTGCTCGCCGTGTGCGCCACGGTGTTGTGTTTTTCACTGATATTCAGGGAACGGTT
ATGTGAGCTGAATATTCACAGAGGAAATACAGTGGTGCAGGTAACTCTGGCCTACGAAGCACGGAAGTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9031.44 Da        Isoelectric Point: 5.6792

>AT231538 WP_039349647.1 NZ_CP090636:917150-917398 [Burkholderia contaminans]
MPHTILANVTASVSELKRNPMGTVAAGEGFPVAILNHNEPAFYCIPAKTWEAMVERLEDIEDNALADKRAKEKVVKVKLN
DL

Download         Length: 249 bp

>AT231538 NZ_CP126927:141874-141935 [Escherichia coli O2:K1:H5]
TTAAGGTACTTCATGCAGACCTCACGAGTTAATGGATTAACGAGTGGGGTCTTCGCATTTCT

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A1E3FLI5

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A4V2WFY1

References