Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vagCD/VagC(antitoxin)
Location 1400813..1401237 Replicon chromosome
Accession NZ_CP090635
Organism Burkholderia contaminans strain FFI45

Toxin (Protein)


Gene name vagD Uniprot ID -
Locus tag LXE92_RS06500 Protein ID WP_223274361.1
Coordinates 1401076..1401237 (+) Length 54 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag LXE92_RS06495 Protein ID WP_105815832.1
Coordinates 1400813..1401079 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LXE92_RS06480 (LXE92_06470) 1396361..1398622 + 2262 WP_278129997.1 TonB-dependent siderophore receptor -
LXE92_RS06485 (LXE92_06475) 1398709..1399548 + 840 WP_278129999.1 formyltransferase family protein -
LXE92_RS06490 (LXE92_06480) 1399548..1400563 + 1016 Protein_1268 GNAT family N-acetyltransferase -
LXE92_RS06495 (LXE92_06485) 1400813..1401079 + 267 WP_105815832.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
LXE92_RS06500 (LXE92_06490) 1401076..1401237 + 162 WP_223274361.1 type II toxin-antitoxin system VapC family toxin Toxin
LXE92_RS06505 (LXE92_06495) 1401387..1401860 - 474 Protein_1271 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
LXE92_RS06510 (LXE92_06500) 1401829..1402917 - 1089 WP_278130000.1 type IV toxin-antitoxin system AbiEi family antitoxin -
LXE92_RS06515 (LXE92_06505) 1403275..1404490 + 1216 Protein_1273 M20 family metallopeptidase -
LXE92_RS06520 (LXE92_06510) 1404607..1404852 + 246 WP_089456200.1 type II toxin-antitoxin system ParD family antitoxin -
LXE92_RS06525 (LXE92_06515) 1404898..1405137 + 240 WP_256946690.1 type II toxin-antitoxin system RelE/ParE family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

SpoVT-AbrB domain

(7-55)


Sequences

Toxin        


Download         Length: 54 a.a.        Molecular weight: 5903.95 Da        Isoelectric Point: 8.5349

>T231533 WP_223274361.1 NZ_CP090635:1401076-1401237 [Burkholderia contaminans]
VTTLYMLDTSICSFIMRERPPVVLSRLQSCVNAQHRIVVSAITYAEMRFGAAG

Download         Length: 162 bp

>T231533 NZ_CP126926:c5095240-5094929 [Escherichia coli O2:K1:H5]
ATGCTCTTCATCGAAACGGAAATTTTTACTGAAGATGTTCAAAAACTGCTGAACGACGATGAATTCAGTCGTTTTCAGTT
TTTCCTGGCCTTGAATCCTGACTATGGTGAGGTAATACCTGAAACTGGTGGGTTAAGAAAGGTTCGATGGGTCTCAGGAG
GAAAGGGGAAACGTGCTGGTGTCAGGGTTATTTACTTTCATCAGGTTAAACATTATGAGATCAGATTACTGCTTATTTAT
CGTAAGGGTATTAAAGATGATCTGTCTCCCCAGGAAAAAGCAATGCTCCGGTTGTTAAATACGAGGTGGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9712.94 Da        Isoelectric Point: 4.4819

>AT231533 WP_105815832.1 NZ_CP090635:1400813-1401079 [Burkholderia contaminans]
MRTVSIFKNARNQAIRIPKDMEFEGVTELEIRREGDTLLLRPVRPTWLSFASEPPADADFLAERPAVIEPGRFDLSDGGG
AAPTESGQ

Download         Length: 267 bp

>AT231533 NZ_CP126926:c5094928-5094638 [Escherichia coli O2:K1:H5]
ATGGATAAGGCACTTTTTGAGCGGTTGACTCACAGCATGGCCCAGATGAATGAAATTATTGAAGGAACGCGACAGCCTTC
ACGGACTTTTGAAGTTGATGCTATGAAAATCAAAGAAATACGCCGCGCTTCAGGGTTGTCACAATCTAAATTTGCCGATC
TTATTTCCGTAAGCGTAGACACGTTGCGTAACTGGGAGCAGGGGCGACGTTCACCGACCGGGCCTGCAAAGGCTTTGCTG
CGAGCGATTGCCAATGATCCGCAACATGTGCTGCAAGCACTTAACCGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References