Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1994189..1994334 Replicon chromosome
Accession NZ_CP090629
Organism Klebsiella pneumoniae isolate KpBO_TO1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1994225..1994327 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1994189..1994334 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0105_RS09865 (L0105_09865) 1989319..1991379 + 2061 WP_004151449.1 oligopeptidase B -
L0105_RS09870 (L0105_09870) 1991383..1992042 - 660 WP_002911407.1 exodeoxyribonuclease X -
L0105_RS09875 (L0105_09875) 1992121..1992351 - 231 WP_002911406.1 DNA polymerase III subunit theta -
L0105_RS09880 (L0105_09880) 1992464..1992838 + 375 WP_004151448.1 CopC domain-containing protein YobA -
L0105_RS09885 (L0105_09885) 1992842..1993711 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
L0105_RS09890 (L0105_09890) 1993728..1994066 + 339 WP_002911404.1 YebY family protein -
- 1994189..1994334 - 146 - - Antitoxin
- 1994225..1994327 + 103 - - Toxin
L0105_RS09895 (L0105_09895) 1994702..1994845 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
L0105_RS09900 (L0105_09900) 1994950..1995918 - 969 WP_004151446.1 VirK/YbjX family protein -
L0105_RS09905 (L0105_09905) 1996075..1996728 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
L0105_RS09910 (L0105_09910) 1996725..1996916 - 192 WP_002911395.1 YebW family protein -
L0105_RS09915 (L0105_09915) 1997014..1997253 - 240 WP_002911393.1 YebV family protein -
L0105_RS09920 (L0105_09920) 1997369..1998802 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T231511 NZ_CP090629:1994225-1994327 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT231511 NZ_CP090629:c1994334-1994189 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References