Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1994188..1994333 Replicon chromosome
Accession NZ_CP090626
Organism Klebsiella pneumoniae isolate KpBO_TO3

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1994224..1994326 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1994188..1994333 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0104_RS09865 (L0104_09865) 1989318..1991378 + 2061 WP_004151449.1 oligopeptidase B -
L0104_RS09870 (L0104_09870) 1991382..1992041 - 660 WP_002911407.1 exodeoxyribonuclease X -
L0104_RS09875 (L0104_09875) 1992120..1992350 - 231 WP_002911406.1 DNA polymerase III subunit theta -
L0104_RS09880 (L0104_09880) 1992463..1992837 + 375 WP_004151448.1 CopC domain-containing protein YobA -
L0104_RS09885 (L0104_09885) 1992841..1993710 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
L0104_RS09890 (L0104_09890) 1993727..1994065 + 339 WP_002911404.1 YebY family protein -
- 1994188..1994333 - 146 - - Antitoxin
- 1994224..1994326 + 103 - - Toxin
L0104_RS09895 (L0104_09895) 1994701..1994844 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
L0104_RS09900 (L0104_09900) 1994949..1995917 - 969 WP_004151446.1 VirK/YbjX family protein -
L0104_RS09905 (L0104_09905) 1996074..1996727 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
L0104_RS09910 (L0104_09910) 1996724..1996915 - 192 WP_002911395.1 YebW family protein -
L0104_RS09915 (L0104_09915) 1997013..1997252 - 240 WP_002911393.1 YebV family protein -
L0104_RS09920 (L0104_09920) 1997368..1998801 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T231492 NZ_CP090626:1994224-1994326 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT231492 NZ_CP090626:c1994333-1994188 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References