Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2431191..2431462 | Replicon | chromosome |
| Accession | NC_011353 | ||
| Organism | Escherichia coli O157:H7 str. EC4115 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2431229..2431332 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2431191..2431462 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ECH74115_RS13080 | 2428348..2429787 | + | 1440 | WP_001302304.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
| ECH74115_RS13085 | 2429905..2430141 | + | 237 | WP_001295499.1 | DUF1480 family protein | - |
| ECH74115_RS13090 | 2430246..2430437 | + | 192 | WP_001296140.1 | YebW family protein | - |
| ECH74115_RS13095 | 2430438..2431094 | - | 657 | WP_000812736.1 | protein-serine/threonine phosphatase | - |
| - | 2431191..2431462 | + | 272 | - | - | Antitoxin |
| - | 2431229..2431332 | - | 104 | - | - | Toxin |
| ECH74115_RS13105 | 2431490..2431831 | - | 342 | WP_000976483.1 | YebY family protein | - |
| ECH74115_RS13110 | 2431844..2432716 | - | 873 | WP_000879314.1 | copper homeostasis membrane protein CopD | - |
| ECH74115_RS13115 | 2432720..2433094 | - | 375 | WP_000168751.1 | CopC domain-containing protein YobA | - |
| ECH74115_RS13120 | 2433233..2433463 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| ECH74115_RS13125 | 2433565..2434221 | + | 657 | WP_000011656.1 | carbon-nitrogen hydrolase family protein | - |
| ECH74115_RS13130 | 2434245..2434907 | + | 663 | WP_000944244.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T23149 NC_011353:c2431332-2431229 [Escherichia coli O157:H7 str. EC4115]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
Antitoxin
Download Length: 272 bp
>AT23149 NC_011353:2431191-2431462 [Escherichia coli O157:H7 str. EC4115]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
