Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1995492..1995637 Replicon chromosome
Accession NZ_CP090623
Organism Klebsiella pneumoniae isolate KpBO_TO5

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1995528..1995630 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1995492..1995637 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0103_RS09870 (L0103_09870) 1990622..1992682 + 2061 WP_004151449.1 oligopeptidase B -
L0103_RS09875 (L0103_09875) 1992686..1993345 - 660 WP_002911407.1 exodeoxyribonuclease X -
L0103_RS09880 (L0103_09880) 1993424..1993654 - 231 WP_002911406.1 DNA polymerase III subunit theta -
L0103_RS09885 (L0103_09885) 1993767..1994141 + 375 WP_004151448.1 CopC domain-containing protein YobA -
L0103_RS09890 (L0103_09890) 1994145..1995014 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
L0103_RS09895 (L0103_09895) 1995031..1995369 + 339 WP_002911404.1 YebY family protein -
- 1995492..1995637 - 146 - - Antitoxin
- 1995528..1995630 + 103 - - Toxin
L0103_RS09900 (L0103_09900) 1996005..1996148 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
L0103_RS09905 (L0103_09905) 1996253..1997221 - 969 WP_004151446.1 VirK/YbjX family protein -
L0103_RS09910 (L0103_09910) 1997378..1998031 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
L0103_RS09915 (L0103_09915) 1998028..1998219 - 192 WP_002911395.1 YebW family protein -
L0103_RS09920 (L0103_09920) 1998317..1998556 - 240 WP_002911393.1 YebV family protein -
L0103_RS09925 (L0103_09925) 1998672..2000105 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T231473 NZ_CP090623:1995528-1995630 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT231473 NZ_CP090623:c1995637-1995492 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References