Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1959505..1959650 Replicon chromosome
Accession NZ_CP090622
Organism Klebsiella pneumoniae strain KP19-3138

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1959541..1959643 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1959505..1959650 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LXT11_RS12140 1954635..1956695 + 2061 WP_004151449.1 oligopeptidase B -
LXT11_RS12145 1956699..1957358 - 660 WP_021440386.1 exodeoxyribonuclease X -
LXT11_RS12150 1957437..1957667 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LXT11_RS12155 1957780..1958154 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LXT11_RS12160 1958158..1959027 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
LXT11_RS12165 1959044..1959382 + 339 WP_002911404.1 YebY family protein -
- 1959505..1959650 - 146 - - Antitoxin
- 1959541..1959643 + 103 - - Toxin
LXT11_RS12170 1960019..1960162 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LXT11_RS12175 1960267..1961235 - 969 WP_004151446.1 VirK/YbjX family protein -
LXT11_RS12180 1961392..1962045 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
LXT11_RS12185 1962042..1962233 - 192 WP_002911395.1 YebW family protein -
LXT11_RS12190 1962331..1962570 - 240 WP_002911393.1 YebV family protein -
LXT11_RS12195 1962686..1964119 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T231455 NZ_CP090622:1959541-1959643 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT231455 NZ_CP090622:c1959650-1959505 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References