Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relB-yefM/YoeB-RelB |
Location | 75607..76123 | Replicon | plasmid p_1 |
Accession | NZ_CP090616 | ||
Organism | Vibrio pelagius strain WXL662 |
Toxin (Protein)
Gene name | relB | Uniprot ID | - |
Locus tag | LZI70_RS19800 | Protein ID | WP_255232962.1 |
Coordinates | 75607..75876 (-) | Length | 90 a.a. |
Antitoxin (Protein)
Gene name | yefM | Uniprot ID | - |
Locus tag | LZI70_RS19805 | Protein ID | WP_255232963.1 |
Coordinates | 75869..76123 (-) | Length | 85 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LZI70_RS19780 (LZI70_19750) | 71147..72055 | + | 909 | WP_255232958.1 | EamA family transporter | - |
LZI70_RS19785 (LZI70_19755) | 72272..72838 | - | 567 | WP_255232959.1 | carboxymuconolactone decarboxylase family protein | - |
LZI70_RS19790 (LZI70_19760) | 72849..73433 | - | 585 | WP_255232960.1 | NAD(P)H-dependent oxidoreductase | - |
LZI70_RS19795 (LZI70_19765) | 74077..75456 | + | 1380 | WP_255232961.1 | nucleobase:cation symporter-2 family protein | - |
LZI70_RS19800 (LZI70_19770) | 75607..75876 | - | 270 | WP_255232962.1 | Txe/YoeB family addiction module toxin | Toxin |
LZI70_RS19805 (LZI70_19775) | 75869..76123 | - | 255 | WP_255232963.1 | type II toxin-antitoxin system prevent-host-death family antitoxin | Antitoxin |
LZI70_RS19810 (LZI70_19780) | 76312..77286 | - | 975 | WP_255232964.1 | DHH family phosphoesterase | - |
LZI70_RS19815 (LZI70_19785) | 77495..78805 | - | 1311 | WP_255232965.1 | DUF1501 domain-containing protein | - |
LZI70_RS19820 (LZI70_19790) | 78802..80442 | - | 1641 | WP_255232966.1 | DUF1800 domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | - | 1..241480 | 241480 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 90 a.a. Molecular weight: 10613.97 Da Isoelectric Point: 8.8578
>T231444 WP_255232962.1 NZ_CP090616:c75876-75607 [Vibrio pelagius]
MSSSQRLLSWTDEAWNDYLYWQTQDKKTLKRVNKLINDVKRSPFEGIGKPEPLKENLSGFWSRRIDETNRLVYAVDDQAI
TVISCRYHY
MSSSQRLLSWTDEAWNDYLYWQTQDKKTLKRVNKLINDVKRSPFEGIGKPEPLKENLSGFWSRRIDETNRLVYAVDDQAI
TVISCRYHY
Download Length: 270 bp
>T231444 NZ_CP126524:2423067-2423807 [Bacillus toyonensis]
TTGACGATCTCTAACATTCGAATTGGCTTATTTATTTTAGCAATCGTTTTTGTAGTTCTTGTTTTCTTTTATTGGAGAAA
TGAAGAGTTGTATGAAGAGAAAAAGCAGCGAATTCGAAAAACTTGGTATGGATTATTCATAACATCAGTCACAGTTTATT
TCATGATTAAAGGAATCGATTTAACCCTCTGGAAAAATTTATTAATGTTCACTGCGATGGTCATTTTCGTTGATATTTCA
TTTATTTTAACACCTAACATTTCGGAAATATGGGGAGCGAAATTTAGCGATATCGGTAAAACTGTTCAATCCATAAAGCG
GTCATTAATCGCTTCAAAAGCAAGAGGGGAAATATATACGAACATTATCCAAAATATTAATCCAGCAGCATTTGGGACGA
TGGAATGGCATACGGAAGAGGAATATACAAAAAGCTTAAACACATTTTTAGATTCATATGGGGAAAAAATCGGAGCGAAA
ATTGTTGTATTTGAAGCAGCGAATGAATTAAATACGGGCTTTCGTGGTATTCGTTCTCAATTTAGTATTACAATACCTAT
AGAGCATATAGAGCAATTGAATGAACAAAAAGCAGTACAAGTAGAAAACGTGGGAATTATACCAGCAAAAATAATGAATG
ATGTTTTTATCGTTATTGATGGGAAGAAGAATAGCCTGCAAGATCGAGATTTTGAAAATGTATATAATTTAACAATACAT
CATAGTTATTTTAGTAAGTAG
TTGACGATCTCTAACATTCGAATTGGCTTATTTATTTTAGCAATCGTTTTTGTAGTTCTTGTTTTCTTTTATTGGAGAAA
TGAAGAGTTGTATGAAGAGAAAAAGCAGCGAATTCGAAAAACTTGGTATGGATTATTCATAACATCAGTCACAGTTTATT
TCATGATTAAAGGAATCGATTTAACCCTCTGGAAAAATTTATTAATGTTCACTGCGATGGTCATTTTCGTTGATATTTCA
TTTATTTTAACACCTAACATTTCGGAAATATGGGGAGCGAAATTTAGCGATATCGGTAAAACTGTTCAATCCATAAAGCG
GTCATTAATCGCTTCAAAAGCAAGAGGGGAAATATATACGAACATTATCCAAAATATTAATCCAGCAGCATTTGGGACGA
TGGAATGGCATACGGAAGAGGAATATACAAAAAGCTTAAACACATTTTTAGATTCATATGGGGAAAAAATCGGAGCGAAA
ATTGTTGTATTTGAAGCAGCGAATGAATTAAATACGGGCTTTCGTGGTATTCGTTCTCAATTTAGTATTACAATACCTAT
AGAGCATATAGAGCAATTGAATGAACAAAAAGCAGTACAAGTAGAAAACGTGGGAATTATACCAGCAAAAATAATGAATG
ATGTTTTTATCGTTATTGATGGGAAGAAGAATAGCCTGCAAGATCGAGATTTTGAAAATGTATATAATTTAACAATACAT
CATAGTTATTTTAGTAAGTAG
Antitoxin
Download Length: 85 a.a. Molecular weight: 9655.77 Da Isoelectric Point: 4.8500
>AT231444 WP_255232963.1 NZ_CP090616:c76123-75869 [Vibrio pelagius]
MRIVSFTEARNSLKSVLDGVVDDADTTVITRRDSEDAVVMSLDYYNSLMETVHLLRSPKNAEHLSRSIEQYRHGKTTERE
LIDE
MRIVSFTEARNSLKSVLDGVVDDADTTVITRRDSEDAVVMSLDYYNSLMETVHLLRSPKNAEHLSRSIEQYRHGKTTERE
LIDE
Download Length: 255 bp
>AT231444 NZ_CP126524:2423920-2424045 [Bacillus toyonensis]
GTGATAAAAGATTATGACAATGATTTTTTTAAAGAAGAAAATGAAGATACAACAGATTTCTCTTTAATCAAAGGAGATAC
GTTGCAGCAAGTAGAAAAGTTAGAAGAAGAATTAAAAAGAAAATGA
GTGATAAAAGATTATGACAATGATTTTTTTAAAGAAGAAAATGAAGATACAACAGATTTCTCTTTAATCAAAGGAGATAC
GTTGCAGCAAGTAGAAAAGTTAGAAGAAGAATTAAAAAGAAAATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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