Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 75607..76123 Replicon plasmid p_1
Accession NZ_CP090616
Organism Vibrio pelagius strain WXL662

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag LZI70_RS19800 Protein ID WP_255232962.1
Coordinates 75607..75876 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LZI70_RS19805 Protein ID WP_255232963.1
Coordinates 75869..76123 (-) Length 85 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LZI70_RS19780 (LZI70_19750) 71147..72055 + 909 WP_255232958.1 EamA family transporter -
LZI70_RS19785 (LZI70_19755) 72272..72838 - 567 WP_255232959.1 carboxymuconolactone decarboxylase family protein -
LZI70_RS19790 (LZI70_19760) 72849..73433 - 585 WP_255232960.1 NAD(P)H-dependent oxidoreductase -
LZI70_RS19795 (LZI70_19765) 74077..75456 + 1380 WP_255232961.1 nucleobase:cation symporter-2 family protein -
LZI70_RS19800 (LZI70_19770) 75607..75876 - 270 WP_255232962.1 Txe/YoeB family addiction module toxin Toxin
LZI70_RS19805 (LZI70_19775) 75869..76123 - 255 WP_255232963.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LZI70_RS19810 (LZI70_19780) 76312..77286 - 975 WP_255232964.1 DHH family phosphoesterase -
LZI70_RS19815 (LZI70_19785) 77495..78805 - 1311 WP_255232965.1 DUF1501 domain-containing protein -
LZI70_RS19820 (LZI70_19790) 78802..80442 - 1641 WP_255232966.1 DUF1800 domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..241480 241480


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(10-89)

Antitoxin

(1-74)


Sequences


Toxin        


Download         Length: 90 a.a.        Molecular weight: 10613.97 Da        Isoelectric Point: 8.8578

>T231444 WP_255232962.1 NZ_CP090616:c75876-75607 [Vibrio pelagius]
MSSSQRLLSWTDEAWNDYLYWQTQDKKTLKRVNKLINDVKRSPFEGIGKPEPLKENLSGFWSRRIDETNRLVYAVDDQAI
TVISCRYHY

Download         Length: 270 bp

>T231444 NZ_CP126524:2423067-2423807 [Bacillus toyonensis]
TTGACGATCTCTAACATTCGAATTGGCTTATTTATTTTAGCAATCGTTTTTGTAGTTCTTGTTTTCTTTTATTGGAGAAA
TGAAGAGTTGTATGAAGAGAAAAAGCAGCGAATTCGAAAAACTTGGTATGGATTATTCATAACATCAGTCACAGTTTATT
TCATGATTAAAGGAATCGATTTAACCCTCTGGAAAAATTTATTAATGTTCACTGCGATGGTCATTTTCGTTGATATTTCA
TTTATTTTAACACCTAACATTTCGGAAATATGGGGAGCGAAATTTAGCGATATCGGTAAAACTGTTCAATCCATAAAGCG
GTCATTAATCGCTTCAAAAGCAAGAGGGGAAATATATACGAACATTATCCAAAATATTAATCCAGCAGCATTTGGGACGA
TGGAATGGCATACGGAAGAGGAATATACAAAAAGCTTAAACACATTTTTAGATTCATATGGGGAAAAAATCGGAGCGAAA
ATTGTTGTATTTGAAGCAGCGAATGAATTAAATACGGGCTTTCGTGGTATTCGTTCTCAATTTAGTATTACAATACCTAT
AGAGCATATAGAGCAATTGAATGAACAAAAAGCAGTACAAGTAGAAAACGTGGGAATTATACCAGCAAAAATAATGAATG
ATGTTTTTATCGTTATTGATGGGAAGAAGAATAGCCTGCAAGATCGAGATTTTGAAAATGTATATAATTTAACAATACAT
CATAGTTATTTTAGTAAGTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9655.77 Da        Isoelectric Point: 4.8500

>AT231444 WP_255232963.1 NZ_CP090616:c76123-75869 [Vibrio pelagius]
MRIVSFTEARNSLKSVLDGVVDDADTTVITRRDSEDAVVMSLDYYNSLMETVHLLRSPKNAEHLSRSIEQYRHGKTTERE
LIDE

Download         Length: 255 bp

>AT231444 NZ_CP126524:2423920-2424045 [Bacillus toyonensis]
GTGATAAAAGATTATGACAATGATTTTTTTAAAGAAGAAAATGAAGATACAACAGATTTCTCTTTAATCAAAGGAGATAC
GTTGCAGCAAGTAGAAAAGTTAGAAGAAGAATTAAAAAGAAAATGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References