Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/RelE-RelB |
| Location | 446094..446653 | Replicon | chromosome |
| Accession | NZ_CP090615 | ||
| Organism | Vibrio pelagius strain WXL662 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | LZI70_RS15795 | Protein ID | WP_255232614.1 |
| Coordinates | 446094..446372 (-) | Length | 93 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | A0A347UR21 |
| Locus tag | LZI70_RS15800 | Protein ID | WP_005398409.1 |
| Coordinates | 446369..446653 (-) | Length | 95 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LZI70_RS15765 (LZI70_15745) | 441379..442028 | - | 650 | Protein_388 | transposase | - |
| LZI70_RS15770 (LZI70_15750) | 442147..442914 | - | 768 | WP_255232611.1 | BRO family protein | - |
| LZI70_RS15775 (LZI70_15755) | 443402..444051 | - | 650 | Protein_390 | transposase | - |
| LZI70_RS15780 (LZI70_15760) | 444177..444515 | + | 339 | WP_255232612.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| LZI70_RS15785 (LZI70_15765) | 444512..444796 | + | 285 | WP_255232613.1 | NadS family protein | - |
| LZI70_RS15790 (LZI70_15770) | 445353..446002 | - | 650 | Protein_393 | transposase | - |
| LZI70_RS15795 (LZI70_15775) | 446094..446372 | - | 279 | WP_255232614.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| LZI70_RS15800 (LZI70_15780) | 446369..446653 | - | 285 | WP_005398409.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| LZI70_RS15805 (LZI70_15785) | 446812..446925 | - | 114 | WP_255232780.1 | hypothetical protein | - |
| LZI70_RS15810 (LZI70_15790) | 447070..447364 | - | 295 | Protein_397 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| LZI70_RS15815 (LZI70_15795) | 447371..447613 | - | 243 | WP_255232615.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| LZI70_RS15820 (LZI70_15800) | 447724..448020 | + | 297 | WP_255232616.1 | antibiotic biosynthesis monooxygenase | - |
| LZI70_RS15825 (LZI70_15805) | 448072..448686 | + | 615 | WP_255232617.1 | LysE family translocator | - |
| LZI70_RS15830 (LZI70_15810) | 448715..448897 | + | 183 | WP_255232618.1 | hypothetical protein | - |
| LZI70_RS15835 (LZI70_15815) | 449119..449817 | + | 699 | WP_255232619.1 | hypothetical protein | - |
| LZI70_RS15840 (LZI70_15820) | 450548..450964 | + | 417 | WP_255232620.1 | hypothetical protein | - |
| LZI70_RS15845 (LZI70_15825) | 451080..451325 | + | 246 | WP_255232621.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 438757..461759 | 23002 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 11004.74 Da Isoelectric Point: 4.4558
>T231443 WP_255232614.1 NZ_CP090615:c446372-446094 [Vibrio pelagius]
MILWEEESLNDREKIFEFLYDFNPDAAEKTDNLIEAKVENLLEQPLMGVQRDRIRGRLLIIPEISMIVSYWIEGDIIRVM
RVLHQKQKFPTD
MILWEEESLNDREKIFEFLYDFNPDAAEKTDNLIEAKVENLLEQPLMGVQRDRIRGRLLIIPEISMIVSYWIEGDIIRVM
RVLHQKQKFPTD
Download Length: 279 bp
>T231443 NZ_CP126524:238565-238915 [Bacillus toyonensis]
TTGATTGTAAAACGCGGCGACGTGTATTTTGCAGACCTTTCCCCAGTTGTTGGTTCTGAGCAAGGAGGCGTTCGTCCGGT
TCTTGTCATTCAAAATGACATCGGAAATCGTTTTAGTCCAACGGTGATTGTAGCGGCTATTACTGCACAGATTCAAAAAG
CGAAATTACCCACTCATGTGGAAATTGATGCGAAAAAGTATGGATTTGAGAGAGATTCTGTTATTTTACTTGAGCAGATT
CGAACAATCGATAAGCAACGCTTAACGGACAAAATCACTCATTTGGATGAAGTGATGATGATTCGTGTAGATGAAGCGTT
ACAAATTAGTTTAGGACTAATAGATTTTTAA
TTGATTGTAAAACGCGGCGACGTGTATTTTGCAGACCTTTCCCCAGTTGTTGGTTCTGAGCAAGGAGGCGTTCGTCCGGT
TCTTGTCATTCAAAATGACATCGGAAATCGTTTTAGTCCAACGGTGATTGTAGCGGCTATTACTGCACAGATTCAAAAAG
CGAAATTACCCACTCATGTGGAAATTGATGCGAAAAAGTATGGATTTGAGAGAGATTCTGTTATTTTACTTGAGCAGATT
CGAACAATCGATAAGCAACGCTTAACGGACAAAATCACTCATTTGGATGAAGTGATGATGATTCGTGTAGATGAAGCGTT
ACAAATTAGTTTAGGACTAATAGATTTTTAA
Antitoxin
Download Length: 95 a.a. Molecular weight: 11069.40 Da Isoelectric Point: 9.2167
>AT231443 WP_005398409.1 NZ_CP090615:c446653-446369 [Vibrio pelagius]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKTLSHDAWLTEQVNLAFEKFDSGKSVFVEHQTAKSR
MEERKARIRNRGKQ
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKTLSHDAWLTEQVNLAFEKFDSGKSVFVEHQTAKSR
MEERKARIRNRGKQ
Download Length: 285 bp
>AT231443 NZ_CP126524:238273-238560 [Bacillus toyonensis]
GTGTCCGAATCAAGTGTAACTACTGAAATCGTGGTTCGGTTGCCAAAGCAAATGGTAACGGAATTGGACGGAATTGGAAA
ACAAGAGAATAAGAATCGCCATGAACTAATTTGCCAGGCAACACAACTGTTATTGCGTCAACATAAGACGAAGAAACGCT
ACCAACATGAATCAATGCGACGTGGGTACATTGAAATGGGAAAAATTAATCTTGGTATTGCATCTGAAGCTTTCTTAGCA
GAGTATGAAGCAGCTCATACGGTAGAACGCTTAGTTAGCGGGGGGTAA
GTGTCCGAATCAAGTGTAACTACTGAAATCGTGGTTCGGTTGCCAAAGCAAATGGTAACGGAATTGGACGGAATTGGAAA
ACAAGAGAATAAGAATCGCCATGAACTAATTTGCCAGGCAACACAACTGTTATTGCGTCAACATAAGACGAAGAAACGCT
ACCAACATGAATCAATGCGACGTGGGTACATTGAAATGGGAAAAATTAATCTTGGTATTGCATCTGAAGCTTTCTTAGCA
GAGTATGAAGCAGCTCATACGGTAGAACGCTTAGTTAGCGGGGGGTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|