Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 393324..393852 Replicon chromosome
Accession NZ_CP090615
Organism Vibrio pelagius strain WXL662

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LZI70_RS15575 Protein ID WP_255232579.1
Coordinates 393324..393614 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LZI70_RS15580 Protein ID WP_255232580.1
Coordinates 393604..393852 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LZI70_RS15545 (LZI70_15525) 388914..389423 - 510 WP_255232575.1 hypothetical protein -
LZI70_RS15550 (LZI70_15530) 389435..389689 - 255 WP_255232576.1 HNH endonuclease signature motif containing protein -
LZI70_RS15555 (LZI70_15535) 390330..391226 + 897 WP_255232577.1 WYL domain-containing protein -
LZI70_RS15560 (LZI70_15540) 391622..392120 - 499 Protein_347 transposase -
LZI70_RS15565 (LZI70_15545) 392218..393198 + 981 WP_255232578.1 DUF559 domain-containing protein -
LZI70_RS15570 (LZI70_15550) 393189..393335 + 147 WP_255232779.1 DUF3265 domain-containing protein -
LZI70_RS15575 (LZI70_15555) 393324..393614 - 291 WP_255232579.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LZI70_RS15580 (LZI70_15560) 393604..393852 - 249 WP_255232580.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
LZI70_RS15585 (LZI70_15565) 394256..394525 + 270 WP_255232581.1 DUF1778 domain-containing protein -
LZI70_RS15590 (LZI70_15570) 394522..395055 + 534 WP_255232582.1 GNAT family N-acetyltransferase -
LZI70_RS15595 (LZI70_15575) 395342..396265 - 924 WP_255232583.1 LysR family transcriptional regulator -
LZI70_RS15600 (LZI70_15580) 396299..397558 - 1260 WP_255232584.1 hydroxymethylglutaryl-CoA reductase -
LZI70_RS15605 (LZI70_15585) 397725..398045 - 321 WP_255232585.1 hypothetical protein -
LZI70_RS15610 (LZI70_15590) 398366..398539 - 174 WP_255232586.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11177.09 Da        Isoelectric Point: 10.6296

>T231441 WP_255232579.1 NZ_CP090615:c393614-393324 [Vibrio pelagius]
MTYKLDFKKSALKEWKKLGSTLQQQFKKKLVERLDNPHVPASKLSGSDNMYKIKLRQSGYRIVYKVEDDVIVVTVLAVGK
RERSGVYRNAMKRLDD

Download         Length: 291 bp

>T231441 NZ_CP126520:2320427-2321167 [Bacillus toyonensis]
TTGACGATCTCTAACATTCGAATTGGCTTATTTATTTTAGCAATCGTTTTTGTAGTTCTTGTTTTCTTTTATTGGAGAAA
TGAAGAGTTGTATGAAGAGAAAAAGCAGCGAATTCGAAAAACTTGGTATGGATTATTCATAACATCAGTCACAGTTTATT
TCATGATTAAAGGAATCGATTTAACCCTCTGGAAAAATTTATTAATGTTCACTGCGATGGTCATTTTCGTTGATATTTCA
TTTATTTTAACACCTAACATTTCGGAAATATGGGGAGCGAAATTTAGCGATATCGGTAAAACTGTTCAATCCATAAAGCG
GTCATTAATCGCTTCAAAAGCAAGAGGGGAAATATATACGAACATTATCCAAAATATTAATCCAGCAGCATTTGGGACGA
TGGAATGGCATACGGAAGAGGAATATACAAAAAGCTTAAACACATTTTTAGATTCATATGGGGAAAAAATCGGAGCGAAA
ATTGTTGTATTTGAAGCAGCGAATGAATTAAATACGGGCTTTCGTGGTATTCGTTCTCAATTTAGTATTACAATACCTAT
AGAGCATATAGAGCAATTGAATGAACAAAAAGCAGTACAAGTAGAAAACGTGGGAATTATACCAGCAAAAATAATGAATG
ATGTTTTTATCGTTATTGATGGGAAGAAGAATAGCCTGCAAGATCGAGATTTTGAAAATGTATATAATTTAACAATACAT
CATAGTTATTTTAGTAAGTAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9078.38 Da        Isoelectric Point: 4.0078

>AT231441 WP_255232580.1 NZ_CP090615:c393852-393604 [Vibrio pelagius]
MTTRILADVAASITELKANPMKVASSAYGEPVAVLNRNEPVFYCVPAKAYEMMMDRLEDLELLAIANERESEESISVNID
DL

Download         Length: 249 bp

>AT231441 NZ_CP126520:2321280-2321405 [Bacillus toyonensis]
GTGATAAAAGATTATGACAATGATTTTTTTAAAGAAGAAAATGAAGATACAACAGATTTCTCTTTAATCAAAGGAGATAC
GTTGCAGCAAGTAGAAAAGTTAGAAGAAGAATTAAAAAGAAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References