Detailed information of TA system TA231440

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/Phd(antitoxin)
• Location: 2824477..2825024
• Replicon: chromosome
• Accession: NZ_CP090614
• Organism: Vibrio pelagius strain WXL662

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: LZI70_RS12885
• Protein ID: WP_255230509.1
• Coordinates: 2824722..2825024 (+)
• Length: 101 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: LZI70_RS12880
• Protein ID: WP_255230507.1
• Coordinates: 2824477..2824734 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LZI70_RS12850 (LZI70_12835)	2820963..2821394	+	432	WP_255230503.1	NUDIX domain-containing protein	-
LZI70_RS12855 (LZI70_12840)	2821409..2821501	+	93	WP_004749136.1	DUF3265 domain-containing protein	-
LZI70_RS12860 (LZI70_12845)	2821689..2823218	-	1530	WP_255230504.1	IS1182 family transposase	-
LZI70_RS12865 (LZI70_12850)	2823372..2824052	+	681	WP_255230505.1	hypothetical protein	-
LZI70_RS12870 (LZI70_12855)	2824075..2824293	-	219	Protein_2409	IS110 family transposase	-
LZI70_RS12875 (LZI70_12860)	2824306..2824395	+	90	WP_255231816.1	DUF3265 domain-containing protein	-
LZI70_RS12880 (LZI70_12865)	2824477..2824734	+	258	WP_255230507.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
LZI70_RS12885 (LZI70_12870)	2824722..2825024	+	303	WP_255230509.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
LZI70_RS12890 (LZI70_12875)	2825242..2825573	+	332	Protein_2413	type II toxin-antitoxin system RelE/ParE family toxin	-
LZI70_RS12895 (LZI70_12880)	2825560..2825874	+	315	WP_255230510.1	DNA-binding transcriptional regulator	-
LZI70_RS12900 (LZI70_12885)	2826154..2826432	-	279	WP_255230512.1	50S ribosomal protein L25	-
LZI70_RS12905 (LZI70_12890)	2826802..2827530	+	729	WP_255230513.1	glycosyltransferase	-
LZI70_RS12910 (LZI70_12895)	2827547..2828365	+	819	Protein_2417	VTT domain-containing protein	-
LZI70_RS12915 (LZI70_12900)	2828425..2829771	-	1347	WP_255230515.1	ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-91)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-69)

Sequences

Toxin

Protein

• Length: 101 a.a.
• Molecular weight: 11639.54 Da
• Isoelectric Point: 5.1765

>T231440 WP_255230509.1 NZ_CP090614:2824722-2825024 [Vibrio pelagius]
MAEVIWTEPALSDLNDIAEYIALENIVAAKQLVQTIFSKVERLQTFPESGRIPPELEHLSYREVVVNPCRVFYKQDGDKV
FVLFVMRVERDLRKFLLGKQ

Nucleotide

• Length: 303 bp

>T231440 NZ_CP126520:238587-238937 [Bacillus toyonensis]
TTGATTGTAAAACGCGGCGACGTGTATTTTGCAGACCTTTCCCCAGTTGTTGGTTCTGAGCAAGGAGGCGTTCGTCCGGT
TCTTGTCATTCAAAATGACATCGGAAATCGTTTTAGTCCAACGGTGATTGTAGCGGCTATTACTGCACAGATTCAAAAAG
CGAAATTACCCACTCATGTGGAAATTGATGCGAAAAAGTATGGATTTGAGAGAGATTCTGTTATTTTACTTGAGCAGATT
CGAACAATCGATAAGCAACGCTTAACGGACAAAATCACTCATTTGGATGAAGTGATGATGATTCGTGTAGATGAAGCGTT
ACAAATTAGTTTAGGACTAATAGATTTTTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9546.04 Da
• Isoelectric Point: 7.3178

>AT231440 WP_255230507.1 NZ_CP090614:2824477-2824734 [Vibrio pelagius]
MKVELVTSLKRQATKILADLHDTKEPVLITEHGKPSAYLVDVDDYESMKNRLAILEGIARGERALADGKVVSHDEAKDKM
SKWLK

Nucleotide

• Length: 258 bp

>AT231440 NZ_CP126520:238295-238582 [Bacillus toyonensis]
GTGTCCGAATCAAGTGTAACTACTGAAATCGTGGTTCGGTTGCCAAAGCAAATGGTAACGGAATTGGACGGAATTGGAAA
ACAAGAGAATAAGAATCGCCATGAACTAATTTGCCAGGCAACACAACTGTTATTGCGTCAACATAAGACGAAGAAACGCT
ACCAACATGAATCAATGCGACGTGGGTACATTGAAATGGGAAAAATTAATCTTGGTATTGCATCTGAAGCTTTCTTAGCA
GAGTATGAAGCAGCTCATACGGTAGAACGCTTAGTTAGCGGGGGGTAA